GR 89696 FUMARATE
GR 89696 FUMARATE Basic information
- Product Name:
- GR 89696 FUMARATE
- Synonyms:
-
- GR 89696 FUMARATE
- 4-([3,4-DICHLOROPHENYL]ACETYL)-3-(1-PYRROLIDINYLMETHYL)-1-PIPERAZINECARBOXYLIC ACID METHYL ESTER FUMARATE
- 4-((3,4-Dichlorophenyl)acetyl)-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylicacidmethylesterfumarate
- GR 89696
- GR 89696 fumarate salt solid
- Methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate fumarate
- GR 89696 fumarate, 10 mM in DMSO
- CAS:
- 126766-32-3
- MF:
- C23H29Cl2N3O7
- MW:
- 530.4
- Mol File:
- 126766-32-3.mol
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GR 89696 FUMARATE Chemical Properties
- storage temp.
- Store at RT
- solubility
- ethanol: 4.0 mg/mL
- form
- solid
- color
- off-white
MSDS
- Language:English Provider:SigmaAldrich
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GR 89696 FUMARATE Usage And Synthesis
Uses
GR 89696 is a selective κ-opioid receptor agonist with anti-nociceptive and neuroprotective properties.
Biological Activity
Highly potent and selective κ -opioid agonist (IC 50 = 0.04 nM) that may be selective for the putative κ 2 receptor. Anti-nociceptive and neuroprotective in vivo .
in vivo
GR 89696 (intramuscular injection, 0.01-0.1 μg/kg) attenuates the scratching response induced by intrathecal morphine (0.03mg) in a dose-dependent manner without affecting the analgesic effect of morphine[1].
GR-896960(subcutaneous injection, 1 mg/kg) reduces cerebral artery infarct volume by 38% in a rat model of permanent focal ischemia[2].
storage
Store at +4°C
GR 89696 FUMARATESupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Shanghai Lollane Biological Technology Co.,Ltd.
- Tel
- 021-52996696，15000506266 15000506266
EMMX Biotechnology LLC
- Tel
- 888-539-0666
- info@emmx.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
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GR 89696 FUMARATE(126766-32-3)Related Product Information
- 1,4-DIFORMYLPIPERAZINE
- 1-(2-PHENYLETHYL)PIPERAZINE
- METHYL PIPERAZINE-1-CARBOXYLATE
- N-Methyl-3-(1-pyrrolidinyl)-1-propanamine
- 1-PIPERAZINECARBOXYLIC ACID
- (3,4-DICHLOROPHENYL)ACETALDEHYDE
- GR 89696 FUMARATE
- 2-AMINOMETHYL PIPERAZINE
- 1-(3-Aminopropyl)pyrrolidine
- N,N-DIETHYL-2-PHENYLACETAMIDE
- N-(HYDROXYMETHYL)PIPERAZINE