BETA-MERCAPTO-BETA,BETA-CYCLOPENTAMETHYLENE-PROPIONYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-ORN-GLY-NH2
BETA-MERCAPTO-BETA,BETA-CYCLOPENTAMETHYLENE-PROPIONYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-ORN-GLY-NH2 Basic information
- Product Name:
- BETA-MERCAPTO-BETA,BETA-CYCLOPENTAMETHYLENE-PROPIONYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-ORN-GLY-NH2
- Synonyms:
-
- PMP-TYR(ME)-ILE-GLN-ASN-CYS-PRO-ORN-GLY-NH2
- [PMP1,TYR(OME)2,ORN8] VASOTOCIN
- me)(2)-orn(8)-
- oxytocin,1-(beta-mercapto-(beta,beta-cyclopentamethylene)propionicacid)-tyr(o
- (D(CH2)(5/1),TYR(ME)2,ORN8)-OXYTOCIN
- [D(CH2)51, TYR(ME)2, ORN8]-VASOTOCIN
- BETA-MERCAPTO-BETA,BETA-CYCLOPENTAMETHYLENE-PROPIONYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-ORN-GLY-NH2
- (D(CH2)51,(METHYL)TYR2,ORN8)-OXYTOCIN
- CAS:
- 77327-45-8
- MF:
- C48H74N12O12S2
- MW:
- 1075.3
- Product Categories:
-
- OxytocinPeptides for Cell Biology
- Oxytocins
- Hormones
- Oxytocin&Vasopressin
- Pituitary Hormones
- Mol File:
- 77327-45-8.mol
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BETA-MERCAPTO-BETA,BETA-CYCLOPENTAMETHYLENE-PROPIONYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-ORN-GLY-NH2 Chemical Properties
- Boiling point:
- 1537.6±65.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- pka
- 12.85±0.70(Predicted)
- form
- solid
- InChIKey
- ZWVZXPFUQHTUKV-SZQHDTAUSA-N
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Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
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BETA-MERCAPTO-BETA,BETA-CYCLOPENTAMETHYLENE-PROPIONYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-ORN-GLY-NH2 Usage And Synthesis
Uses
[β-Mercapto-β,β-cyclopentamethylenepropionyl1, O-Me-Tyr2, Orn8]-Oxytocin has been used as an oxytocin receptor antagonist:
- to study the influence of blockading the oxytocin receptors in the anterior cingulate cortex on helping behavior
- to determine the receptors that mediate vasopressin-stimulated anion secretion across cultured porcine vas deferens epithelial cell monolayers
- to study the influence of oxytocin receptors inhibition on intravenous and in situ oxytocin effects on the urinary bladder and cardiovascular activities in sham rats
Biochem/physiol Actions
[β-Mercapto-β,β-cyclopentamethylenepropionyl1, O-Me-Tyr2, Orn8]-also acts as an arginine vasopressin receptor 1A (AVPR1A) antagonist.
BETA-MERCAPTO-BETA,BETA-CYCLOPENTAMETHYLENE-PROPIONYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-ORN-GLY-NH2Supplier
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Sigma-Aldrich
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