(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione Chemical Properties

Melting point:

146-148 °C

Boiling point:

413.5±25.0 °C(Predicted)

Density 

1.32±0.1 g/cm3(Predicted)

pka

-0.85±0.20(Predicted)

(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione Usage And Synthesis

Uses

L-Proline Anhydride is an impurity of Vildagliptin (V305000), a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from their use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.

(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione(6708-06-1)Related Product Information

• vildagliptin Impurity E
• Vildagliptin Related Compound H
• Vildagliptin iMpurity K
• Vildagliptin Dione Impurity
• Vildagliptin impurity 1
• Vildagliptin D7
• Vildagliptin Impurity 6
• Vildagliptin Related Compound F
• (R)-1-(2-chloroacetyl)pyrrolidine-2-carboxaMide
• Vildagliptin IMpurity 2 (Mixture of DiastereoMers)
• Vildagliptin Impurity 69
• vildagliptin Impurity Q
• Vildagliptin Impurity 25
• (5aR,10aR)-1,2,3,5a,6,7,8,10a-octahydrodipyrrolo[1,2-c:1',2'-f]pyrazine-5,10-dione
• Dichloroacetyl chloride
• 2-Pyrrolidinecarbonitrile,1-acetyl-,(2S)-(9CI)
• N-acetic acid-1-aMino-3-adaMantanol
• Vildagliptin Impurity 19