(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione

Product Name: (5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione
CAS No.: 6708-06-1
Chemical Name: (5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione
Synonyms: Cyclo(Pro-Pro-);Cyclo(L-Pro-L-Pro-);L-Proline Anhydride;Aliskiren Impurity 50;cis-cyclo(?-Pro-?-Pro);Vildagliptin Impurity 23;Vildagliptin Impurity 60;Vildagliptin impurities12;Vildagliptin Dipyrrolidine Impurity;Proline cyclization impurity (mixed isomers)
CBNumber: CB42182070
Molecular Formula: C10H14N2O2
Formula Weight: 194.23
MOL File: 6708-06-1.mol

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(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione Property

Melting point:: 146-148 °C
Boiling point:: 413.5±25.0 °C(Predicted)
Density: 1.32±0.1 g/cm3(Predicted)
pka: -0.85±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom

Product number: CFN90270
Product name: Cyclo(Pro-Pro)
Packaging: 10mg
Price: $332
Updated: 2021/12/16

AccelPharmtech

Product number: E0942
Product name: octahydro-5H,10H-Dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione
Purity: 97.00%
Packaging: 5G
Price: $1080
Updated: 2021/12/16

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(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione Chemical Properties,Usage,Production

Uses

L-Proline Anhydride is an impurity of Vildagliptin (V305000), a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from their use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.

(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione Preparation Products And Raw materials

Raw materials

Preparation Products

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(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione Suppliers

China 41 India 4 United States 5 Global 50

ForeChem (Nantong) Technology Co.,Ltd.

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Nanjing Digger Medical Technology Co. Ltd.

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6708-06-1, (5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dioneRelated Search:

vildagliptin Impurity E Vildagliptin Related Compound H Vildagliptin iMpurity K Vildagliptin Dione Impurity Vildagliptin impurity 1 Vildagliptin D7 Vildagliptin Impurity 6 Vildagliptin Related Compound F (R)-1-(2-chloroacetyl)pyrrolidine-2-carboxaMide Vildagliptin IMpurity 2 (Mixture of DiastereoMers) Vildagliptin Impurity 69 vildagliptin Impurity Q Vildagliptin Impurity 25 (5aR,10aR)-1,2,3,5a,6,7,8,10a-octahydrodipyrrolo[1,2-c:1',2'-f]pyrazine-5,10-dione Dichloroacetyl chloride 2-Pyrrolidinecarbonitrile,1-acetyl-,(2S)-(9CI) N-acetic acid-1-aMino-3-adaMantanol Vildagliptin Impurity 19

(5aS,10aS)-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aH)-dione

(5aS,10aS)-Octahydro-5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione

1,2,3,5aβ,6,7,8,10aβ-Octahydro-5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione

Cyclo(L-Pro-L-Pro-)

Cyclo(Pro-Pro-)

Vildagliptin Impurity 60

Vildagliptin Impurity 23

Octahydro-5H,10H-Dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione

Vildagliptin Impurity 17/Vildagliptin Dipyrrolidine Impurity/octahydro-5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione

Vildagliptin Dipyrrolidine Impurity

1,7-diazatricyclo[7.3.0.03,7]dodecane-2,8-dione

5H,10H-Dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione, octahydro-

L-Proline Anhydride

Vildagliptin impurities12

cis-cyclo(?-Pro-?-Pro)

Aliskiren Impurity 50

Proline cyclization impurity (mixed isomers)

Octahydro-5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione

Pyroglutamic acid lactam impurity (mixed isomers)

6708-06-1