Basic information Safety Supplier Related

Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester

Basic information Safety Supplier Related

Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester Basic information

Product Name:
Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester
Synonyms:
  • Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester
  • PA-1
  • PA1 2HCl
  • PA-1 2HCl,PA1 2HCl
CAS:
1620951-72-5
MF:
C32H50O7Sn2
MW:
784.1552
Mol File:
1620951-72-5.mol
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Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester Chemical Properties

storage temp. 
-196°C
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Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester Usage And Synthesis

Uses

PA1 is a photoswitchable epithelial sodium channel (ENaC) blocker. PA1 can switch to cis-PA1 at 400nm and trans-PA1 at 500nm. PA1 inhibits δ/αENaC, αβγENaC, and δβγENaC, with IC50 values of 4.3nM, 90 nM, and 390 nM, respectively[1].

References

[1] Matthias Sch?nberger, et al. Controlling epithelial sodium channels with light using photoswitchable amilorides. Nat Chem. 2014 Aug;6(8):712-9. DOI:10.1038/nchem.2004

Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl esterSupplier

Hangzhou Peptidego Biotech Co.,Ltd.
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TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
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Shanghai guandao biology engineering co., ltd
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18818239863
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Wuhan Sunncell Biotech Co., Ltd.
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Shanghai Bolsen Biotechnology Co., LTD
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