(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester Chemical Properties

Boiling point:

568.8±50.0 °C(Predicted)

Density 

1.281±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 10 mg/ml

pka

13.43±0.20(Predicted)

(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester Usage And Synthesis

Description

Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals.¹ The isopropyl ester of fluprostenol (travoprost) is an effective ocular hypotensive drug.²

Uses

Fluprostenol methyl ester is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals[1].

References

1. Dukes, M., Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F_2α Nature 250(464),330-331(1974).
2. Sorbera, L.A., and Casta?er, J. Travoprost Drugs Future 25(1),41-45(2000).

(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester(73275-76-0)Related Product Information

• (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide
• (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester