1,4-BUTANEDIPHOSPHONIC ACID Chemical Properties

Melting point:

219-221 °C

Boiling point:

544.4±60.0 °C(Predicted)

Density 

1.641±0.06 g/cm3(Predicted)

storage temp. 

Storage temp. 2-8°C

form 

Fine Powder

pka

2.26±0.10(Predicted)

color 

White

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

45-36/37/39-25

RIDADR 

UN 3261 8/PG III

HazardClass 

8

PackingGroup 

III

HS Code 

29319019

MSDS

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1,4-BUTANEDIPHOSPHONIC ACID Usage And Synthesis

Chemical Properties

white fine powder

Uses

Butane-1,4-diyldiphosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

Alkyl-Chain

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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