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CLODRONIC ACID

Basic information Safety Supplier Related

CLODRONIC ACID Basic information

Product Name:
CLODRONIC ACID
Synonyms:
  • CLODRONIC ACID
  • Disodium diphosphonate
  • Clodronic
  • (Dichloromethylene)bis(phosphonic acid)
  • ARC-69931
  • Dichloromethylenebis(phosphonic acid)
  • Dichloromethylenebisphosphonic acid
  • Aids071014
CAS:
10596-23-3
MF:
CH4Cl2O6P2
MW:
244.89
EINECS:
234-212-1
Mol File:
10596-23-3.mol
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CLODRONIC ACID Chemical Properties

Melting point:
249-251°
Boiling point:
474.7±55.0 °C(Predicted)
Density 
2.306±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
Solid
pka
0.75±0.10(Predicted)
color 
Off-white to light yellow
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CLODRONIC ACID Usage And Synthesis

Uses

Regulator (calcium).

Uses

Clodronic Acid is a bisphosphonate that can be used in the treatment of osteoporosis. Its ATP-analogs can inhibit cell signaling pathways.

Definition

ChEBI: An organochlorine compound that is methylene chloride in which both hydrogens are replaced by phosphonic acid groups. It inhibits bone resorption and soft tissue calcification, and is used (often as the disodium salt tetrahydrate) as an adjunct in the trea ment of severe hypercalcaemia associated with malignancy, and in the management of osteolytic lesions and bone pain associated with skeletal metastases.

CLODRONIC ACIDSupplier

Hotechem Shanghai Co., Ltd., Gold
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Suizhou Jiake Biological Engineering Co., Ltd. Gold
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NCE Biomedical Co.,Ltd.
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