M-NISOLDIPINE
M-NISOLDIPINE Basic information
- Product Name:
- M-NISOLDIPINE
- Synonyms:
-
- M-NISOLDIPINE
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl 5-(2-methylpropyl) ester
- 3-Methyl 5-(2-methylpropyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
- 3-methyl 5-(2-methylpropyl) 2
- 4-dihydropyridine-3
- 6-dimethyl-4-(3-nitrophenyl)-1
- m-Nisolpidine
- m Nisoldipine,mNisoldipine
- CAS:
- 113578-26-0
- MF:
- C20H24N2O6
- MW:
- 388.41
- Mol File:
- 113578-26-0.mol
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M-NISOLDIPINE Chemical Properties
- Melting point:
- 122-124 °C
- Boiling point:
- 505.8±50.0 °C(Predicted)
- Density
- 1.205±0.06 g/cm3(Predicted)
- pka
- 2.69±0.70(Predicted)
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M-NISOLDIPINE Usage And Synthesis
Uses
m-Nisoldipine (KR-1008) is a dihydropyridine calcium antagonist that can significantly increase cardiac output and heart index, significantly reduce the negative inotropic effect on the myocardium, and has a relatively high selectivity for the thoracic aorta. m-Nisoldipine can be used in the research of cardiovascular diseases[1].
Definition
ChEBI: M-Nisoldipine is a dihydropyridine.
References
[1] Yang C, et al. Thermodynamic stability analysis of m-nisoldipine polymorphs[J]. The Journal of Chemical Thermodynamics, 2013, 58: 300-306.
M-NISOLDIPINESupplier
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