Palonidipine
Palonidipine Basic information
- Product Name:
- Palonidipine
- Synonyms:
-
- Palonidipine
- 1,4-Dihydro-4-(2-fluoro-5-nitrophenyl)-2,6-dimethylpyridine-3,5-dicarboxylic acid 3-[3-(N-benzylmethylamino)-2,2-dimethylpropyl]5-methyl ester
- 1,4-Dihydro-4-(2-fluoro-5-nitrophenyl)-2,6-dimethylpyridine-3,5-dicarboxylic acid 3-methyl 5-[3-[benzyl(methyl)amino]-2,2-dimethylpropyl] ester
- 3-O-[2,2-dimethyl-3-[methyl(phenylmethyl)amino]propyl] 5-O-methyl 4-(2-fluoro-5-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
- 4-(2-fluoro-5-nitro-phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid O3-[3-[benzyl(methyl)amino]-2,2-dimethyl-propyl] ester O5-methyl ester
- O3-[2,2-dimethyl-3-[methyl(phenylmethyl)amino]propyl] O5-methyl 4-(2-fluoro-5-nitro-phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
- 5-O-[3-[benzyl(methyl)amino]-2,2-dimethylpropyl] 3-O-methyl 4-(2-fluoro-5-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
- 3,5-Pyridinedicarboxylic acid, 4-(2-fluoro-5-nitrophenyl)-1,4-dihydro-2,6-dimethyl-, 3-[2,2-dimethyl-3-[methyl(phenylmethyl)amino]propyl] 5-methyl ester
- CAS:
- 96515-73-0
- MF:
- C29H34FN3O6
- MW:
- 539.6
- Mol File:
- 96515-73-0.mol
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Palonidipine Chemical Properties
- Boiling point:
- 619.1±55.0 °C(Predicted)
- Density
- 1.216±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 8.26±0.50(Predicted)
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Palonidipine Usage And Synthesis
Uses
Palonidipine is a calcium antagonist which is potential for the therapy of angina-pectoris and hypertension[1][2][3].
References
[1] Okamiya Y, et al. [Effect of palonidipine hydrochloride (TC-81), a novel calcium antagonist, on the canine coronary artery]. Nihon Yakurigaku Zasshi. 1993 Jul;102(1):23-33. DOI:10.1254/fpj.102.23
[2] Kishimoto T, et al. [Effect of palonidipine hydrochloride (TC-81), a new dihydropyridine derivative, on various myocardial ischemic models]. Nihon Yakurigaku Zasshi. 1993 Aug;102(2):85-100. DOI:10.1254/fpj.102.85
[3] K. Sunakawa, et al. Effects of palonidipine hydrochloride on respiratory and cardiovascular systems. January 1993
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