(3S)-3-[[3-[[4-(TRIFLUOROMETHYL)BENZOYL]AMINO]PHENYL]METHOXY]-L-ASPARTIC ACID Chemical Properties

Boiling point:

513.6±50.0 °C(Predicted)

Density 

1.500±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

Soluble to 100 mM in DMSO

form 

Powder

pka

2.05±0.27(Predicted)

color 

White to off-white

(3S)-3-[[3-[[4-(TRIFLUOROMETHYL)BENZOYL]AMINO]PHENYL]METHOXY]-L-ASPARTIC ACID Usage And Synthesis

Uses

TFB-TBOA is a novel glutamate transporter blocker.

Biological Activity

High affinity, selective blocker of glial glutamate transporters EAAT1 and EAAT2 (IC 50 values are 17, 22 and 300 nM for EAAT2, EAAT1 and EAAT3 respectively). Displays no activity on a wide range of neurotransmitter receptors and transporters. Induces convulsions following i.c.v. administration in mice.

storage

Store at -20°C

(3S)-3-[[3-[[4-(TRIFLUOROMETHYL)BENZOYL]AMINO]PHENYL]METHOXY]-L-ASPARTIC ACID(480439-73-4)Related Product Information

• (3S)-3-[[3-[[4-(TRIFLUOROMETHYL)BENZOYL]AMINO]PHENYL]METHOXY]-L-ASPARTIC ACID
• DL-THREO-BETA-HYDROXYASPARTIC ACID