DL-THREO-BETA-HYDROXYASPARTIC ACID Chemical Properties

Melting point:

>230°C dec

Boiling point:

368.7±42.0 °C(Predicted)

Density 

1.738±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

Aqueous Base (Slightly)

pka

2.13±0.27(Predicted)

form 

Solid

color 

White to Pale Beige

Stability:

Hygroscopic

InChIKey

YYLQUHNPNCGKJQ-JCYAYHJZSA-N

CAS DataBase Reference

4294-45-5

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

DL-THREO-BETA-HYDROXYASPARTIC ACID Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

A glutamate uptake inhibitor

Uses

L-aspartate beta-carboxylase inhibitor, neurotoxic

Uses

DL-threo-β-Hydroxyaspartic acid (THA) has been used to block glutamate transport in cannulated sprague dawley rat.

Definition

ChEBI: (3S)-3-hydroxy-L-aspartic acid is the (3S)-diastereomer of 3-hydroxy-L-aspartic acid. It has a role as a metabolite. It is a conjugate acid of a (3S)-3-hydroxy-L-aspartate(2-) and a (3S)-3-hydroxy-L-aspartate(1-). It is an enantiomer of a (3R)-3-hydroxy-D-aspartic acid.

General Description

DL-threo-β-hydroxyaspartic acid (THA) is a glutamate uptake inhibitor.

DL-THREO-BETA-HYDROXYASPARTIC ACID(4294-45-5)Related Product Information

• empedopeptin
• DL-TBOA
• (3S)-3-[[3-[[4-(TRIFLUOROMETHYL)BENZOYL]AMINO]PHENYL]METHOXY]-L-ASPARTIC ACID
• DIMETHYL THREO-HYDROXY-D,L-ASPARTATE
• D -(+)-THREO -BETA-HYDROXYASPARTIC ACID
• erythro-3-hydroxy-DL-aspartic acid
• DIMETHYL N-TERT-BUTOXYCARONYL-3-HYDROXYASPARTATE
• (2R,3S)-2-amino-3-hydroxy-succinic acid
• DL-THREO-BETA-HYDROXYASPARTIC ACID