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3-BROMOIMIDAZO[1,2-A]PYRIDINE

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3-BROMOIMIDAZO[1,2-A]PYRIDINE Basic information

Product Name:
3-BROMOIMIDAZO[1,2-A]PYRIDINE
Synonyms:
  • 3-BROMOIMIDAZO[1,2-A]PYRIDINE
  • BUTTPARK 96\50-11
  • 3-Bromoimidazo[1,2-a]pyridine, 95+%
  • 3-Bromopyrimidazole
  • Imidazo[1,2-a]pyridine, 3-bromo- (7CI,8CI,9CI)
  • NSC 305197
  • IMidazo[1,2-a]pyridine, 3-broMo-
  • 3-Bromoimidazo[1,2-a]pyridine 97%
CAS:
4926-47-0
MF:
C7H5BrN2
MW:
197.03
Product Categories:
  • Fused Ring Systems
  • Imidazopyridines
  • Building Blocks
  • C7 to C18
  • C7 to C8
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyridines
  • Halides
Mol File:
4926-47-0.mol
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3-BROMOIMIDAZO[1,2-A]PYRIDINE Chemical Properties

Melting point:
92 °C
Density 
1.69±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
solid
pka
3.85±0.50(Predicted)
Appearance
Light yellow to brown Solid
InChI
1S/C7H5BrN2/c8-6-5-9-7-3-1-2-4-10(6)7/h1-5H
InChIKey
APYSHMNJHJRIDR-UHFFFAOYSA-N
SMILES
Brc1cnc2ccccn12
CAS DataBase Reference
4926-47-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
T,Xi,Xn
Risk Statements 
20/21/22-22
Safety Statements 
22-36/37/39
WGK Germany 
WGK 2
HazardClass 
IRRITANT
HS Code 
2933399990
Storage Class
11 - Combustible Solids
Hazard Classifications
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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3-BROMOIMIDAZO[1,2-A]PYRIDINE Usage And Synthesis

Uses

3-Bromoimidazo[1,2-a]pyridine is an azaheterocyclic compound containing a bromine atom in its molecular structure, which can be used in electrophilic substitution reactions to prepare other organic products.

Synthesis

To a stirred solution of imidazole (1,2)-pyridine (500 ??L, 4.9 mmol) in DMF (5 mL) was added N-bromosuccinimide (878 mg, 4.9 mmol). The resulting solution was stirred at room temperature for 5 min. The reaction mixture was diluted with water (50 mL) and extracted with ethyl acetate (2x30mL). The combined organic layers were washed with brine, dried over magnesium sulfate and concentrated to give 3-bromoimidazo[1,2-A]pyrimidine as a white solid in a yield of 730 mg, 73%.

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