Basic information Safety Supplier Related

2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione

Basic information Safety Supplier Related

2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione Basic information

Product Name:
2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione
Synonyms:
  • 2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione
  • 4-Nitrothalidomide
  • Pomalidomide Intermediates
  • Pomalidomide Impurity E
  • 4-nitro-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
  • 2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindole-1,3-dione
  • Thalidomide 4-Nitro Impurity
  • 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-nitro-
CAS:
19171-18-7
MF:
C13H9N3O6
MW:
303.23
EINECS:
200-258-5
Mol File:
19171-18-7.mol
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2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione Chemical Properties

Melting point:
>200°C (dec.)
Boiling point:
603.4±50.0 °C(Predicted)
Density 
1.651±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Acetonitrile (Slightly, Heated, Sonicated), DMSO (Slightly)
pka
10.55±0.40(Predicted)
form 
Solid
color 
Pale Yellow to Pale Beige
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2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione Usage And Synthesis

Uses

4-Nitrothalidomide is a compound involved in the preparation of Pomalidomide (P688200), a thalidomide derivative and potent inhibitor of TNF-α production.

2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dioneSupplier

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