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5-Fluoro ent-LaMivudine Acid D-Menthol Ester

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5-Fluoro ent-LaMivudine Acid D-Menthol Ester Basic information

Product Name:
5-Fluoro ent-LaMivudine Acid D-Menthol Ester
Synonyms:
  • 5-Fluoro ent-LaMivudine Acid D-Menthol Ester
  • Emtricitabine impurity 8/5-Fluoro ent-Lamivudine Acid D-Menthol Ester/(2S,5R)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid (1S,2R,5S)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester
  • (2S,5R)-(1S,2R,5S)-2-Isopropyl-5-Methylcyclohexyl 5-(4-aMino-5-fluoro-2-oxopyriMidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
  • (5S)-(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
  • Emtricitabine Impurity V
  • (5S)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1
  • 1,3-Oxathiolane-2-carboxylic acid, 5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-, (1S,2R,5S)-5-methyl-2-(1-methylethyl)cyclohexyl ester, (2S,5R)-
  • (1s,2r,5s)-2-Isopropyl-5-methylcyclohexyl (2s,5r)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2h)-yl)-1,3-oxathiolane-2-carboxylate
CAS:
764659-79-2
MF:
C18H26FN3O4S
MW:
399.48
Product Categories:
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Carbohydrates & Derivatives
  • Chiral Reagents
  • Pharmaceuticals
  • Carbohydrates & Derivatives, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
764659-79-2.mol
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5-Fluoro ent-LaMivudine Acid D-Menthol Ester Chemical Properties

Melting point:
189-191°C
Boiling point:
508.5±60.0 °C(Predicted)
Density 
1.47±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
2.40±0.10(Predicted)
form 
Solid
color 
White to Off-White
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Safety Information

HS Code 
2933599590
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5-Fluoro ent-LaMivudine Acid D-Menthol Ester Usage And Synthesis

Chemical Properties

White Solid

Uses

Intermediate in the synthesis of ent-Emtricitabine (E525005).

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