(8α,9S)-9-aMino-Cinchonan-6'-ol Chemical Properties

alpha 

+107.9° (c 1.0, CHCl3)

Boiling point:

501.7±45.0 °C(Predicted)

Density 

1.24±0.1 g/cm3(Predicted)

pka

8.92±0.40(Predicted)

form 

Powder

color 

off-white to pale brown

Stability:

store cold

(8α,9S)-9-aMino-Cinchonan-6'-ol Usage And Synthesis

Reaction

1. [2+3]-dipolar cycloaddition of cyclic enones.
2. Activation of α,β-unsaturated carbonyl compounds:
 a) vinylogous α-ketol rearrangement.
 b) vinylogous Michael addition of β-substituted α,β-unsaturated cyclohexanones.
3. Michael addition
 a) α-nitroacetate to α,β-unsaturated ketones.
 b) Diastereodivergent Michael addition to α-substituted, α,β-unsaturated ketones.
4. α-benzoyloxylation of α-branched aldehydes.
5. [4+2]-cycloadditions of β-substituted α,β-unsaturated cyclohexanones with polyconjugated malonitriles.
6. Vinylogous organocascade catalysis with control of remote stereochemistry in the synthesis of spirocyclic oxindoles.

(8α,9S)-9-aMino-Cinchonan-6'-ol(960050-59-3)Related Product Information

• Quinine
• (8α,9R)- 9-(9-phenanthrenyloxy)-Cinchonan-6'-ol
• 6'-hydroxydihydrocinchonidine
• O-Desmethyl Quinine
• 9-Amino-(9-deoxy)epi-quinine trihydrochloride
• (8α,9R)- 9-(phenylMethoxy)-Cinchonan-6'-ol
• 9-Amino-(9-deoxy)epi-dihydroquinine trihydrochloride
• 9-Amino-(9-deoxy)epi-cinchonidine trihydrochloride