O-Desmethyl Quinine Chemical Properties

Melting point:

>171°C (dec.)

alpha 

D17 -176°

Boiling point:

450.55°C (rough estimate)

Density 

1.1396 (rough estimate)

refractive index 

1.5600 (estimate)

storage temp. 

-20°C Freezer

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

6.57(at 25℃)

form 

Solid

color 

Off-White to Pale Yellow

InChI

InChI=1/C19H22N2O2/c1-2-12-11-21-8-6-13(12)9-18(21)19(23)15-5-7-20-17-4-3-14(22)10-16(15)17/h2-5,7,10,12-13,18-19,22-23H,1,6,8-9,11H2/t12-,13+,18+,19-/s3

InChIKey

VJFMSYZSFUWQPZ-HQKGGXQFNA-N

SMILES

N12CC[C@@]([C@H](C=C)C1)([H])C[C@@]2([H])[C@H](O)C1=CC=NC2C=CC(O)=CC1=2 |&1:3,4,10,12,r|

O-Desmethyl Quinine Usage And Synthesis

Chemical Properties

Pale Yellow Solid

Uses

A metabolite of Quinine (Q694000).

Definition

One of the cinchona alkaloids.

Purification Methods

Cupreine crystallises from EtOH (anhydrous crystals) and wet Et2O (as dihydrate crystals). It has Kb 2.7x10-7 [Kolthoff Biochem Z 162 323]. The sulfate forms needles, m 257o(dec), from MeOH, amyl alcohol or H2O, with [] 20-197.9o (c 1.2, H2O). [Beilstein 22 I 165, 22 II 416.]

O-Desmethyl Quinine(524-63-0)Related Product Information

• O-Desmethyl Quinidine
• Copper sulfate basic
• (8α,9R)- 9-(9-phenanthrenyloxy)-Cinchonan-6'-ol
• 6'-hydroxydihydrocinchonidine
• 9-Amino-(9-deoxy)epi-quinine trihydrochloride
• (8α,9S)-9-aMino-Cinchonan-6'-ol
• (8α,9R)- 9-(phenylMethoxy)-Cinchonan-6'-ol
• 9-Amino-(9-deoxy)epi-dihydroquinine trihydrochloride
• 9-Amino-(9-deoxy)epi-cinchonidine trihydrochloride
• (1S,2S,5S)-2-(HYDROXYMETHYL)-5-VINYLQUINUCLIDINE
• QUININE BISULFATE HEPTAHYDRATE
• Quinine
• O-Desmethyl Quinine