ChemicalBook > Product Catalog > Biochemical Engineering > Biochemical Reagents > Agonist Inhibitors > Ledipasvir (acetone)
Ledipasvir (acetone)
Ledipasvir (acetone) Basic information
- Product Name:
- Ledipasvir (acetone)
- Synonyms:
-
- Ledipasvir Acetone Adducts
- Ledipasvir(GS-5885) acetone
- Ledipasvir acetone complex
- Ledipasvir (acetone)
- Ledipasvir acetone solvate
- Mono Acetone Solvate of Ledipasvir
- Ledipasvir compd. with acetone
- GS 5885 acetone
- CAS:
- 1441674-54-9
- MF:
- C52H60F2N8O7
- MW:
- 947.1
- Mol File:
- 1441674-54-9.mol
More
Less
Ledipasvir (acetone) Chemical Properties
- storage temp.
- 4°C, protect from light
- solubility
- DMSO: ≥ 39 mg/mL (41.18 mM)
- form
- Powder
- color
- Off-white to yellow
More
Less
Ledipasvir (acetone) Usage And Synthesis
Uses
Ledipasvir acetone (GS-5885 acetone) is the active ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.
References
[1] Link JO, et al. Discovery of ledipasvir (GS-5885): a potent, once-daily oral NS5A inhibitor for the treatment of hepatitis C virus infection. J Med Chem. 2014 Mar 13;57(5):2033-46. DOI:10.1021/jm401499g
Ledipasvir (acetone)Supplier
Chembest Research Laboratories Limited
- Tel
- +86-21-20908456
- sales@BioChemBest.com
Jiangsu Vcare PharmaTech Co., Ltd.
- Tel
- 025-58741518 13327700685
- sales@vcarepharmatech.com
Hunan Hui Bai Shi Biotechnology Co., Ltd.
- Tel
- 0731-85526065 13308475853
- ivy@hnhbsj.com
Haoyuan Chemexpress Co., Ltd.
- Tel
- 021-58950125
- info@chemexpress.com
Acesys Pharmatech
- Tel
- 18860950986
- tangmanman@zenjipharma.com