CALP3 Chemical Properties

storage temp. 

Desiccate at -20°C

form 

Powder

color 

White to off-white

Water Solubility 

Soluble to 1 mg/ml in water

CALP3 Usage And Synthesis

Uses

CALP3, a Ca2+-like peptide, is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. CALP3 can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin (CaM), Ca2+ channels and pumps. CALP3 has the potential in controlling apoptosis in diseases such as AIDS or neuronal loss due to ischemia[1][2].

References

[1] Manion MK, et al. A new type of Ca(2+) channel blocker that targets Ca(2+) sensors and prevents Ca(2+)-mediated apoptosis. FASEB J. 2000 Jul;14(10):1297-306. DOI:10.1096/fj.14.10.1297
[2] Ferdek PE, et al. BH3 mimetic-elicited Ca2+ signals in pancreatic acinar cells are dependent on Bax and can be reduced by Ca2+-like peptides. Cell Death Dis. 2017 Mar 2;8(3):e2640. DOI:10.1038/cddis.2017.41

CALP3(261969-05-5)Related Product Information

• calcium-like peptide CALP1
• calcium-like peptide CALP3
• CALP,CALP1
• CALP2
• CALPONIN,34KD,CLONE:CALP,MABANTI-HUMAN
• CALPONIN,34KD,CLONE:CALP,MABANTI-HUMAN,RAT:PARAFFIN,IH
• calcium-like peptide CALP2
• CALP3
• Aminobutyroyl hexapeptide-8
• Oligopeptide-30