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1-[5-O-(4,4'-DIMETHOXYTRITYL)-3-O-NITROPHENYLSULFONYL-2-DEOXY-BETA-D-LYXOFURANOSYL]THYMINE

Basic information Safety Supplier Related

1-[5-O-(4,4'-DIMETHOXYTRITYL)-3-O-NITROPHENYLSULFONYL-2-DEOXY-BETA-D-LYXOFURANOSYL]THYMINE Basic information

Product Name:
1-[5-O-(4,4'-DIMETHOXYTRITYL)-3-O-NITROPHENYLSULFONYL-2-DEOXY-BETA-D-LYXOFURANOSYL]THYMINE
Synonyms:
  • 1-[5-O-(4,4'-DIMETHOXYTRITYL)-3-O-NITROPHENYLSULFONYL-2-DEOXY-BETA-D-LYXOFURANOSYL]THYMINE
  • 5'-O-DIMETHOXYTRITYL-3'-O-NOSYL-THYMIDINE
  • NON-BOC-FLT
  • 1-[5-O-(4,4''-Dimethoxytrityl)-3-O-nitrophenylsulfonyl-2-deoxy-beta-
  • DMTr-Nosyl-lyxothymidine
  • 1-(2'-Deoxy-5'-O-DMT-3'-O-nitrophenylsulphonyl-b-D-lyxofuranosyl)thymine
  • 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-3-O-[(4-nitrophenyl)sulfonyl]-beta-D-threo-pentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
  • 2,4(1H,3H)-PYRIMIDINEDIONE, 1-[5-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2-DEOXY-3-O-[(4-NITROPHENYL)SULFONYL]-BETA-D-THREO-PENTOFURANOSYL]-5-METHYL-
CAS:
444717-20-8
MF:
C37H35N3O11S
MW:
729.75
Mol File:
444717-20-8.mol
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1-[5-O-(4,4'-DIMETHOXYTRITYL)-3-O-NITROPHENYLSULFONYL-2-DEOXY-BETA-D-LYXOFURANOSYL]THYMINE Chemical Properties

Melting point:
122 °C
Density 
1.45±0.1 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
9.55±0.10(Predicted)
color 
Light Orange to Orange
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1-[5-O-(4,4'-DIMETHOXYTRITYL)-3-O-NITROPHENYLSULFONYL-2-DEOXY-BETA-D-LYXOFURANOSYL]THYMINE Usage And Synthesis

Chemical Properties

Yellowish amorphous solid

Uses

1-(2'-Deoxy-5'-O-DMT-3'-O-nitrophenylsulphonyl-b-D-lyxofuranosyl)thymine (CAS# 444717-20-8) is an intermediate in the synthesis of 3-N-Boc-5'-O-DMT-3'-O-Nosyl Thymidine (N212160), used in the radio-synthesis of 18F-labeled deoxyfluorothymidine as radiopharmaceutical for PET by fluorination via nucleophilic substitution of precursor.

1-[5-O-(4,4'-DIMETHOXYTRITYL)-3-O-NITROPHENYLSULFONYL-2-DEOXY-BETA-D-LYXOFURANOSYL]THYMINESupplier

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