mPEG5-t-buyl ester
mPEG5-t-buyl ester Basic information
- Product Name:
- mPEG5-t-buyl ester
- Synonyms:
-
- mPEG5-t-buyl ester
- m-PEG5-t-butyl ester
- mPEG5-CH2CH2COOtBu
- m-PEG5-Boc
- 4,7,10,13,16-Pentaoxaheptadecanoic acid, 1,1-dimethylethyl ester
- tert-butyl 2,5,8,11,14-pentaoxaheptadecan-17-oate
- m-PEG5-COOtBu
- CAS:
- 874208-93-2
- MF:
- C16H32O7
- MW:
- 336.42
- Mol File:
- 874208-93-2.mol
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mPEG5-t-buyl ester Chemical Properties
- solubility
- Soluble in DMSO, DMF, DCM
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mPEG5-t-buyl ester Usage And Synthesis
Description
m-PEG5-t-buyl ester is a PEG linker containing a t-butyl ester. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
m-PEG5-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] Balasingam Radhakrishnan, et al. Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof. US20060018874A1.
mPEG5-t-buyl esterSupplier
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