ChemicalBook > Product Catalog > Biochemical Engineering > Biochemical Reagents > Agonist Inhibitors > MX-69
MX-69
MX-69 Basic information
- Product Name:
- MX-69
- Synonyms:
-
- MX-69
- CS-2402
- MX69 (MX 69
- Benzoic acid, 4-[8-[[(3,4-dimethylphenyl)amino]sulfonyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]-
- E1/E2/E3 Enzyme,inhibit,E3 ligating enzyme,MX 69,Ubiquitin ligase,IAP,MX69,E1 activating enzyme,E2 conjugating enzyme,Ubiquitin conjugating enzyme,MX-69,Inhibitor,Ubiquitin activating enzyme,MDM-2/p53
- 4-(8-(N-(3,4-Dimethylphenyl)sulfamoyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)benzoic acid
- MX69, 10 mM in DMSO
- MX69 ，S8403
- CAS:
- 1005264-47-0
- MF:
- C27H26N2O4S
- MW:
- 474.57
- Mol File:
- 1005264-47-0.mol
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MX-69 Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMSO: soluble
- form
- A solid
- color
- White to off-white
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MX-69 Usage And Synthesis
Uses
MX69 is an inhibitor of MDM2/XIAP, used for cancer treatment.
in vivo
MX69-induced MDM2 downregulation results in activation of p53 which contributes to inhibition of cancer cell proliferation in vivo[1].
References
[1] Lubing Gu, et al. Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment. Cancer Cell. 2016 Oct 10;30(4):623-636 DOI:10.1016/j.ccell.2016.08.015
[2] Gu L, et al. Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment. Cancer Cell. 2016 Oct 10;30(4):623-636
MX-69Supplier
Dalian Meilun Biotech Co., Ltd.
- Tel
- 0411-62910999 13889544652
- sales@meilune.com
Guangzhou Isun Pharmaceutical Co., Ltd
- Tel
- 020-39119399 18927568969
- isunpharm@qq.com
Bide Pharmatech Ltd.
- Tel
- 400-400-164-7117 18317119277
- product02@bidepharm.com
Shanghai Lollane Biological Technology Co.,Ltd.
- Tel
- 021-52996696，15000506266 15000506266
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com