ChemicalBook > Product Catalog > Biochemical Engineering > Biochemical Reagents > Agonist Inhibitors > BAY41-4109 Racemic
BAY41-4109 Racemic
BAY41-4109 Racemic Basic information
- Product Name:
- BAY41-4109 Racemic
- Synonyms:
-
- BAY41-4109 Racemic
- Bay 41-4109 (racemate)
- Methyl 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoropyridin-2-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxylate
- BAY41-4109 RACEMATE; BAY-41-4109 RACEMATE
- 5-Pyrimidinecarboxylic acid, 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-1,4-dihydro-6-methyl-, methyl ester
- 4-?(2-Chloro-?4-?fluorophenyl)?-?2-?(3,?5-?difluoro-?2-?pyridinyl)?-?1,?4-?dihydro-?6-?methyl-?5-?pyrimidinecarboxylic Acid Methyl Ester
- Bay 41-4109,Inhibitor,HBV,Bay 41 4109 racemate,inhibit,Bay 414109 racemate,Hepatitis B virus
- Bay 41-4109 racemate, 10 mM in DMSO
- CAS:
- 298708-79-9
- MF:
- C18H13ClF3N3O2
- MW:
- 395.76
- Product Categories:
-
- API
- Mol File:
- 298708-79-9.mol
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BAY41-4109 Racemic Chemical Properties
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMSO:89.5(Max Conc. mg/mL);226.14(Max Conc. mM)
Ethanol:11.0(Max Conc. mg/mL);27.79(Max Conc. mM) - form
- A crystalline solid
- color
- Light yellow to yellow
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BAY41-4109 Racemic Usage And Synthesis
Uses
4-(2-Chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic Acid Methyl Ester is an antiviral compound that inhibits HBV replication by destabilizing capsid assembly.
in vivo
BAY 41-4109 reduces viral DNA in the liver and in the plasma dose-dependently with efficacy comparable to 3TC. BAY 41 -4109 reduces hepatitis B virus core antigen (HBcAg) in livers of HBV-transgenic mice. Pharmacokinetic studies in mice have shown rapid absorption, a bioavailability of 30% and dose-proportional plasma concentrations, about 60% in rats and dogs[1].BAY41-4109 inhibits virus production in vivo by a mechanism that targets the viral capsid[2].
BAY41-4109 RacemicSupplier
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
- Tel
- 025-66113011 17798518460
- cfzhang@aikonchem.com
Cool Pharm, Ltd
- Tel
- 021-60455363 18019463053
- sales@coolpharm.com
Shanghai Lollane Biological Technology Co.,Ltd.
- Tel
- 021-52996696，15000506266 15000506266
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
Tianjin Kailiqi Biotechnology Co., Ltd.
- Tel
- 15076683720
- klq@cw-bio.com