(S)-(-)-ALPHA-METHYL-1-NAPHTHALENEMETHANOL
(S)-(-)-ALPHA-METHYL-1-NAPHTHALENEMETHANOL Basic information
- Product Name:
- (S)-(-)-ALPHA-METHYL-1-NAPHTHALENEMETHANOL
- Synonyms:
-
- (S)-(-)-1-(1-NAPHTHYL)ETHANOL
- (S)-1-NAPHTHALEN-1-YL-ETHANOL
- (S)-(-)-ALPHA-METHYL-1-NAPHTHALENEMETHANOL
- (s)-(-)-α-methyl-1-naphthalenemethanol
- s-(-)-α-methyl-1-naphthalenemethanol
- S-(-)-1-(1-NAPTHALENYL)ETHANOL
- (S)-1-Naphthylethanol
- (1S)-1-(1-Naphthyl)ethanol
- CAS:
- 15914-84-8
- MF:
- C12H12O
- MW:
- 172.22
- EINECS:
- 1592732-453-0
- Product Categories:
-
- Alcohols, Hydroxy Esters and Derivatives
- Chiral Compounds
- Mol File:
- 15914-84-8.mol
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(S)-(-)-ALPHA-METHYL-1-NAPHTHALENEMETHANOL Chemical Properties
- Melting point:
- 47-49 °C(lit.)
- alpha
- -77 º (C=1 IN MEOH)
- Boiling point:
- 165°C/11mmHg(lit.)
- Density
- 1.113±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 14.29±0.20(Predicted)
- form
- Powder
- color
- Yellow
- optical activity
- [α]20/D 77°, c = 1 in methanol
- BRN
- 2045009
- InChI
- InChI=1/C12H12O/c1-9(13)11-8-4-6-10-5-2-3-7-12(10)11/h2-9,13H,1H3/t9-/s3
- InChIKey
- CDRQOYRPWJULJN-DJEYLCQNNA-N
- SMILES
- C12C=CC=CC=1C=CC=C2[C@@H](O)C |&1:10,r|
- CAS DataBase Reference
- 15914-84-8(CAS DataBase Reference)
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MSDS
- Language:English Provider:SigmaAldrich
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(S)-(-)-ALPHA-METHYL-1-NAPHTHALENEMETHANOL Usage And Synthesis
Chemical Properties
White fine crystalline powder
Uses
(S)?-?1-?(Naphthalen-?1-?yl)?ethanol is a building block used in the synthesis of novel 2,4-diaminoquinazoline derivatives as SMN2 promoter activators for the potential treatment of spinal muscular atrophy.
Purification Methods
Purify the alcohol by recrystallisation from Et2O/pet ether, Et2O, hexane [Balfe et al. J Chem Soc 797 1946, IR, NMR: Theisen & Heathcock J Org Chem 53 2374 1988, see also Fredga et al. Acta Chem Scand 11 1609 1957]. The RS-alcohol [57605-95-5] has m 63-65o, 65-66o from hexane. [Beilstein 6 III 3034, 6 IV 4346.]
(S)-(-)-ALPHA-METHYL-1-NAPHTHALENEMETHANOLSupplier
Shanghai Rochi Pharmaceutical Co., Ltd. Gold
- Tel
- 021-38751876 15000076078
- Info@rochipharma.com
Shanghai RC biotechnology Ltd. Gold
- Tel
- 021-18217521994; 18217521994
- 1809424504@qq.com
Hebei Zhoukun Pharmaceutical Technology Co., LTD Gold
- Tel
- 0311-83784138 18633934202
- zhoukunpharma@163.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Alfa Aesar
- Tel
- 400-6106006
- saleschina@alfa-asia.com
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(S)-(-)-ALPHA-METHYL-1-NAPHTHALENEMETHANOL(15914-84-8)Related Product Information
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- BPDE-III
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- CHRYSENE-TRANS-5,6-DIHYDRODIOL
- TRANS-9,10-DIHYDRO-9,10-DIHYDROXY-6-NITROCHRYSENE