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20-O-Demethyl-AP3

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20-O-Demethyl-AP3 Basic information

Product Name:
20-O-Demethyl-AP3
Synonyms:
  • ANSAMITOCIN DERIV
  • PDM3
  • Mertansine Impurity 4
  • 20-O-Demethyl-AP3
  • Ansamitocin derivative TN-006
  • Maytansine, 2'-de(acetylmethylamino)-O20-demethyl-2'-methyl- (9CI)
  • Maytansine, 2'-de(acetylmethylamino)-O(20)-demethyl-2'-methyl
  • (1S,2R,3S,5S,6R,16E,18E,20R,21S)-11-chloro-12,21-dihydroxy-20-methoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.11?,1?.03,?]hexacosa-10,12,14(26),16,18-pentaen-6-yl 2-methylpropanoate
CAS:
72902-38-6
MF:
C31H41ClN2O9
MW:
621.12
Mol File:
72902-38-6.mol
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20-O-Demethyl-AP3 Chemical Properties

Boiling point:
845.8±65.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
pka
8.08±0.70(Predicted)
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20-O-Demethyl-AP3 Usage And Synthesis

Description

20-O-Demethyl-AP3 is a secondary metabolite derived from Ansamitocin P-3, and Ansamitocin P-3 is a macrocyclic antitumor antibiotic exerting its therapeutic effects by inhibiting microtubules.

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