1-Hexanol, 6,6'-oxybis[2,2-dimethyl-
1-Hexanol, 6,6'-oxybis[2,2-dimethyl- Basic information
- Product Name:
- 1-Hexanol, 6,6'-oxybis[2,2-dimethyl-
- Synonyms:
-
- 1-Hexanol, 6,6'-oxybis[2,2-dimethyl-
- Hydrocarbon chain derivative 1
- 6,6'-Oxybis[2,2-dimethyl-1-hexanol]
- 2-dimethyl-1-hexanol
- 6'-Oxybis[2
- CAS:
- 300762-25-8
- MF:
- C16H34O3
- MW:
- 274.43936
- Mol File:
- 300762-25-8.mol
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1-Hexanol, 6,6'-oxybis[2,2-dimethyl- Chemical Properties
- Boiling point:
- 160-162 °C(Press: 0.15 Torr)
- Density
- 0.933±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 14.91±0.10(Predicted)
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1-Hexanol, 6,6'-oxybis[2,2-dimethyl- Usage And Synthesis
Uses
Hydrocarbon chain derivative 1 is an active compound, with inhibitory activities against lipid synthesis.
in vivo
Hydrocarbon chain derivative 1 is well tolerated with mild liver effects at 2000 mg/kg in rats[1]. Hydrocarbon chain derivative 1 shows inhibitory effect on lipid synthesis, with an IC50 of 11 μM[2].
References
[1] Oniciu DC, et al. Influence of various central moieties on the hypolipidemic properties of long hydrocarbon chain diols and diacids. J Med Chem. 2006 Jan 12;49(1):334-48. DOI:10.1021/jm050650j
[2] Oniciu DC, et al. Long hydrocarbon chain diols and diacids with central ether or ketone moieties that favorably alter lipid disorders. Pharmazie. 2006 Feb;61(2):157-65. PMID:16526566
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