DECANOIC-D19 ACID Chemical Properties

Melting point:

30-32 °C(lit.)

Boiling point:

268-270 °C(lit.)

Density 

0.991 g/mL at 25 °C

storage temp. 

-20°C Freezer, Under inert atmosphere

solubility 

Methanol (Slightly), Water (Slightly)

form 

Solid

color 

White to Off-White

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

DECANOIC-D19 ACID Usage And Synthesis

Description

Decanoic acid-d₁₉ is intended for use as an internal standard for the quantification of decanoic acid by GC- or LC-MS. Decanoic acid is a medium-chain saturated fatty acid. It is a non-competitive antagonist at AMPA receptors that selectively reduces glutamate-induced currents in Xenopus oocytes expressing GluA2 and GluA3 subunit-containing AMPA receptors (IC₅₀ = 0.52 mM) over those expressing GluA1 (IC₅₀ = 2.09 mM) or GluA1 and GluA2 subunits (IC₅₀ = 1.16 mM). It inhibits epileptiform activity induced by pentylenetetrazole or low magnesium in rat hippocampal slices. Decanoic acid (1 mM) induces contractions in isolated guinea pig duodenum, an effect that can be blocked by the muscarinic acetylcholine receptor antagonist hyoscine, voltage-gated sodium channel inhibitor tetrodotoxin (Item Nos. 14964 | 14963), or M₂ muscarinic acetylcholine receptor antagonist hexamethonium . It increases the escape threshold in an orofacial mechanical stimulation test in rats when administered at a topical dose of 30% in ointment form, indicating analgesic activity. This effect can be blocked by the muscarinic acetylcholine receptor antagonist methoctramine . Plasma levels of decanoic acid are increased in patients with colorectal cancer when compared to patients with breast cancer or ulcerative colitis or without cancer.

Uses

Decanoic-d19 Acid is used on platinum-on-carbon-catalyzed multiple deuterium labeling of saturated fatty acids. Cylindrocyclophane biosynthesis involves functionalization of an unactivated carbon center.

DECANOIC-D19 ACID(88170-22-3)Related Product Information

• HEPTANOIC-5,5,6,6-D4 ACID
• N-DECYL-9,9,10,10,10-D5 ALCOHOL
• DECANOIC-10,10,10-D3 ACID
• DECANOIC-D19 ACID
• N-NONYL-6,6,7,7-D4 ALCOHOL
• HEXANOIC-5,5-D2 ACID
• SODIUM DECANOATE-D19
• METHYL DECANOATE-D19