Basic information Safety Supplier Related

4-HYDROXYESTRONE

Basic information Safety Supplier Related

4-HYDROXYESTRONE Basic information

Product Name:
4-HYDROXYESTRONE
Synonyms:
  • 1,3,5[10]-ESTRATRIENE-3,4-DIOL-17-ONE
  • 1,3,5(10)-ESTRATRIEN-3,4-DIOL-17-ONE
  • 3,4-DIHYDROXY-1,3,5[10]-ESTRATRIEN-17-ONE
  • 4-HYDROXYESTRONE
  • 3,4-dihydroxyestra-1,3,5(10)-trien-17-one
  • 5(10)-trien-17-one,3,4-dihydroxy-estra-3
  • (9S,14S)-3,4-dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
  • Estrone 4-Hydroxy Impurity
CAS:
3131-23-5
MF:
C18H22O3
MW:
286.37
Product Categories:
  • Various Metabolites and Impurities
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Steroids
Mol File:
3131-23-5.mol
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4-HYDROXYESTRONE Chemical Properties

Melting point:
260-263°C
Boiling point:
468.2±45.0 °C(Predicted)
Density 
1.241±0.06 g/cm3(Predicted)
Flash point:
93 °C
storage temp. 
−20°C
solubility 
DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
form 
Solid
pka
10.06±0.40(Predicted)
color 
Pale Yellow to Light Brown
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Safety Information

WGK Germany 
3
RTECS 
KG7749500

MSDS

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4-HYDROXYESTRONE Usage And Synthesis

Chemical Properties

Pale Yellow Solid

Uses

A metabolite of Estradiol.

Definition

ChEBI: A 4-hydroxy steroid that is estrone substituted by a hydroxy group at position 4.

Hazard

A reproductive hazard.

Biochem/physiol Actions

4-Hydroxyestrone is an endogenous estrogen metabolite, which exhibits a strong neuroprotective effect against oxidative damage. It also provides effective protection against kanic acid-induced hippocampal oxidative damage in rats when compared to 17β-estradiol. 4-Hydroxyestrone regulates the angiogenic process during corpus luteum formation. It might be involved in an increased risk of cancer. 4-Hydroxyestrone is found in the early and mid-luteal phases.

4-HYDROXYESTRONESupplier

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Clearsynth Labs Limited
Tel
+91-22-26355700
Email
info@clearsynth.com
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Email
sales@chem-strong.com
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
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4-HYDROXYESTRONE(3131-23-5)Related Product Information