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TOTU

Basic information Safety Supplier Related

TOTU Basic information

Product Name:
TOTU
Synonyms:
  • O-[(ETHOXYCARBONYL)CYANOMETHYLENAMINO]-N,N,N',N'-TETRAMETHYLURONIUM TETRAFLUOROBORATE
  • O-[(ETHOXYCARBONYL)-CYANOMETHYLENEAMINO]-1,1,3,3-TETRAMETHYLURONIUM TETRAFLUOROBORATE
  • O-((Ethoxycarbonyl)cyanomethyleneamino)-N,N,N',N'-tetramethyluronium BF4
  • O-[(ETHOXYCARBONYL)CYANOMETHYLENEAMINO]-N,N,N',N'-TETRAMETHYLURONIUM TETRAFLUOROBORATE
  • O-[(ETHOXYCARBOXYL)CYANOMETHYLENEAMINO]-N,N,N',N'-TETRAMETHYLURONIUM TETRAFLUOROBORATE
  • O-(CYANO(ETHOXYCARBONYL)METHYLENAMINO)-1,1,3,3-TETRAMETHYLURONIUM TETRAFLUOROBORATE
  • TOTU
  • 2-CYANOETHOXYCARBONYLMETHYLIDENEAMINO-1,1,3,3-TETRAMETHYLURONIUMTETRAFLUOROBORATE
CAS:
136849-72-4
MF:
C10H17BF4N4O3
MW:
328.07
EINECS:
629-020-3
Product Categories:
  • Coupling Reagent
Mol File:
136849-72-4.mol
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TOTU Chemical Properties

Melting point:
145 °C (dec.)(lit.)
storage temp. 
2-8°C
solubility 
Soluble in water or 1% acetic acid
form 
Crystalline Powder
color 
White to yellow
Sensitive 
Moisture Sensitive
InChI
InChI=1S/C10H17N4O3.BF4/c1-6-16-9(15)8(7-11)12-17-10(13(2)3)14(4)5;2-1(3,4)5/h6H2,1-5H3;/q+1;-1/b12-8-;
InChIKey
PZOBERLGEQHZDV-BPWZRWDXSA-M
SMILES
C(=[N+](/C)\C)(\N(C)C)/O/N=C(/C#N)\C(=O)OCC.[B-](F)(F)(F)F
CAS DataBase Reference
136849-72-4(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
RIDADR 
1759
WGK Germany 
3
8-10-21
HazardClass 
8
PackingGroup 
III
HS Code 
29280000
Toxicity
LD50 orally in Rabbit: 500 - 650 mg/kg

MSDS

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TOTU Usage And Synthesis

Chemical Properties

white to yellowish crystalline powder

Uses

Reactant for:
Watson-Crick pairing of oligonucleotides
Esterification of nucleosides to solid phase supports
Reagent for:
Synthesis of selective integrin avβ3 antagonists
Design and synthesis of double stranded DNA libraries
Preparation of conformationally contrained β-amino acid derivatives
Synthesis and application of methyleneoxy pseudopeptide building blocks

reaction suitability

reaction type: Coupling Reactions

TOTUSupplier

Suzhou Highfine Biotech Co., Ltd Gold
Tel
0512-69209928 18796809688
Email
zhouyingxiang@highfine.com
Binhai gill polypeptide co. LTD Gold
Tel
021-61263389 13524856427
Email
Joetang@glschina.com
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Email
jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Email
market03@meryer.com
Alfa Aesar
Tel
400-6106006
Email
saleschina@alfa-asia.com