Basic information Safety Supplier Related

VALNEMULIN

Basic information Safety Supplier Related

VALNEMULIN Basic information

Product Name:
VALNEMULIN
Synonyms:
  • VALNEMULIN
  • 2-[[2-[[(2R)-2-Amino-3-methyl-1-oxobutyl]amino]-1,1-dimethylethyl]thio]acetic Acid (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-Ethenyldecahydro-5-hydroxy-4,6,9,10- tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl Ester
  • supplier valnemulin
  • Acetic acid, 2-[[2-[[(2R)-2-amino-3-methyl-1-oxobutyl]amino]-1,1-dimethylethyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester
  • Acetic acid,[[2-[[(2R)-2-amino-3-methyl-1-oxobutyl]amino]-1,1-dimethylethyl]thio]-,(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-ylester
CAS:
101312-92-9
MF:
C31H52N2O5S
MW:
564.82
EINECS:
1312995-182-4
Product Categories:
  • API
  • Heterocyclic Compounds
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Alphabetic
  • Antibiotics
  • Chemical Structure
  • OthersAnalytical Standards
  • V
  • Diterpenes antibiotic
Mol File:
101312-92-9.mol
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VALNEMULIN Chemical Properties

Melting point:
140-143°C
Boiling point:
672.7±55.0 °C(Predicted)
Density 
1.13±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form 
A solid
pka
14.65±0.70(Predicted)
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VALNEMULIN Usage And Synthesis

Description

Valnemulin is a broad-spectrum pleuromutilin antibiotic that binds to peptidyl transferase in the 50S ribosomal subunit. It has been used in veterinary medicine to treat swine diseases including, B. hyodysenteriae and M. hyopneumoniae.

Chemical Properties

White to Off-White Solid

Uses

Semisynthetic antibiotic; derivative of pleuromutilin. Antibacterial

Uses

Valnemulin is a semi-synthetic pleuromutilin prepared by sequential reaction of pleuromutilin tosylate with 2-amino-1,1-dimethylethylthiol, coupling the free amine with a protected valine and then deprotection to provide the final product. Valnemulin is a broad spectrum antibiotic used to control gastrointestinal infections in animals and shows no cross resistance to other antibiotic classes. Like all the pleuromutilins, valnemulin inhibits protein synthesis by binding to domain V of 23S RNA.

VALNEMULINSupplier

shilang(zhuoli group)-pharma(nanjing) co.,ltd.
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86-25-87797880,81,82 -809
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shilang@shilang-pharma.com
Chemsky (shanghai) International Co.,Ltd
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021-50135380
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shchemsky@sina.com
Sichuan Wei Keqi Biological Technology Co., Ltd.
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028-81700200 18116577057
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3003855609@qq.com
Taizhou Creating Chemical Co., Ltd
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0576-88827176 18906581668
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sonya@creatingchemical.com
Wuhan Dahua Pharmaceutical Co., Ltd.
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027-59262863 13277907145 3091977954