5,7-DIHYDROXY-3',4',5'-TRIMETHOXYFLAVONE Chemical Properties

Melting point:

266-276°C

Boiling point:

562.4±50.0 °C(Predicted)

Density 

1.387±0.06 g/cm3(Predicted)

pka

6.47±0.40(Predicted)

5,7-DIHYDROXY-3',4',5'-TRIMETHOXYFLAVONE Usage And Synthesis

Uses

Tricetin 3',4',5'-trimethyl ether (5,7-Dihydroxy-3',4',5'-trimethoxyflavone) is a flavone glucoside, that can be isolated the flowers of Chrysanthemum sinensea. Tricetin 3',4',5'-trimethyl ether displays xanthine oxidase competitive-type inhibitory activity, with an IC50 of 0.51 μM and a Ki of 0.37 μM[1].

Definition

ChEBI: A trimethoxyflavone that is the 3',4',5'-tri-O-methyl ether of tricetin.

References

[1] Nguyen MT, Awale S, Tezuka Y, Ueda JY, Tran Ql, Kadota S. Xanthine oxidase inhibitors from the flowers of Chrysanthemum sinense. Planta Med. 2006 Jan;72(1):46-51. DOI:10.1055/s-2005-873181

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