Basic information Safety Supplier Related

STEFFIMYCIN B

Basic information Safety Supplier Related

STEFFIMYCIN B Basic information

Product Name:
STEFFIMYCIN B
Synonyms:
  • STEFFIMYCIN B
  • 1,6,11(2h)-naphthacenetrione,4-((6-deoxy-2,4-di-o-methyl-alpha-l-mannopyranosy
  • 5,7-trihydroxy-3,9-dimethoxy-2-methyl-l)oxy)-4-dihydro-2
  • u40615
  • 4-(2-O,4-O-Dimethyl-α-L-rhamnopyranosyloxy)-3,4-dihydro-2,5,7-trihydroxy-3,9-dimethoxy-2-methyl-1,6,11(2H)-naphthacenetrione
  • 4-[(2-O,4-O-Dimethyl-6-deoxy-α-L-mannopyranosyl)oxy]-3,4-dihydro-2,5,7-trihydroxy-3,9-dimethoxy-2-methyl-1,6,11(2H)-naphthacenetrione
  • Steffimycin 4'-methyl ether
  • 1,6,11(2H)-Naphthacenetrione, 4-((6-deoxy-2,4-di-o-methyl-alpha-L-mannopyranosyl)oxy)-3,4-dihydro-2,5,7-trihydroxy-3,9-dimethoxy-2-methyl-
CAS:
54526-94-2
MF:
C29H32O13
MW:
588.56
Mol File:
54526-94-2.mol
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STEFFIMYCIN B Chemical Properties

Boiling point:
801.2±65.0 °C(Predicted)
Density 
1.52±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form 
A lyophilisate
pka
5.09±0.70(Predicted)
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STEFFIMYCIN B Usage And Synthesis

Uses

Steffimycin B is an anthracycline metabolite isolated from a Streptomyces sp., with antibacterial and antineoplastic properties. Crystallographic studies of binding to DNA suggest that it has a higher CpG base sequence specificity over the TpA step, similar to that of daunorubicin and nogalamycin. A close analogue was shown to be active against ras oncogene-expressed cells.

STEFFIMYCIN BSupplier

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