Remibrutinib
Remibrutinib Basic information
- Product Name:
- Remibrutinib
- Synonyms:
-
- LOU064
- LOU-064
- REMIBRUTINIB
- N-(3-{5-[2-(Acryloyl-methyl-amino)-ethoxy]-6-amino-pyrimidin-4-yl}-5-fluoro-2-methyl-phenyl)-4-cyclopropyl-2-fluoro-benzamide
- Benzamide, N-[3-[6-amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluoro-
- Remibrutinib (LOU064)
- N-(3-(6-Amino-5-(2-(N-methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide
- Btk,Inhibitor,inhibit,Remibrutinib,Bruton tyrosine kinase
- CAS:
- 1787294-07-8
- MF:
- C27H27F2N5O3
- MW:
- 507.53
- Mol File:
- 1787294-07-8.mol
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Remibrutinib Chemical Properties
- Boiling point:
- 634.8±55.0 °C(Predicted)
- Density
- 1.332±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 125 mg/mL (246.29 mM)
- form
- Solid
- pka
- 11.67±0.70(Predicted)
- color
- White to off-white
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Remibrutinib Usage And Synthesis
Description
Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib has the potential for Chronic urticaria (CU) treatment.
Chemical Properties
White to off-white Solid
RemibrutinibSupplier
Nantong QuanYi Biotechnology Co., Ltd Gold
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Shanghai XingMo Biotechnology Co., Ltd. Gold
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Shanghai Hope Chem Co., Ltd.， Gold
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Bayee Biotech (Anqing) Co., Ltd. Gold
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Sichuan Wei Keqi Biological Technology Co., Ltd.
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- 028-81700200 18116577057
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