CLOMIPRAMINE-D3
CLOMIPRAMINE-D3 Basic information
- Product Name:
- CLOMIPRAMINE-D3
- Synonyms:
-
- CLOMIPRAMINE-D3
- 5H-Dibenzb,fazepine-5-propanamine, 3-chloro-10,11-dihydro-N-methyl-N-(methyl-d3)-
- CLOMIPRAMINE-D3,100/MLINMETHANOL
- [2H3]-Clomipramine HCl
- [2H3]-Clomipramine
- CAS:
- 136765-29-2
- MF:
- C18H19ClD3N3
- MW:
- 318.86
- EINECS:
- 604-604-1
- Mol File:
- 136765-29-2.mol
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CLOMIPRAMINE-D3 Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
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CLOMIPRAMINE-D3 Usage And Synthesis
Uses
Clomipramine-d3 is the deuterium labeled Clomipramine. Clomipramine is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2].
References
[1] McTavish, D. and P. Benfield, Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder. Drugs, 1990. 39(1): p. 136-53. DOI:10.2165/00003495-199039010-00010
[2] Owens, M.J., et al., Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther, 1997. 283(3): p. 1305-22. PMID:9400006
CLOMIPRAMINE-D3Supplier
MedChemexpress LLC
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ChemStrong Scientific Co.,Ltd
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- 0755-0755-66853366 13670046396
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Shanghai Champ Biopharmaceuticals Co., Ltd.
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- 021-61537865 13585780846
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Amadis Chemical Company Limited
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- 571-89925085
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Chengdu Novel Biomedical Co., Ltd.
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- 028-85255396 18302801538
- cdnovell@163.com