MS4078
MS4078 Basic information
- Product Name:
- MS4078
- Synonyms:
-
- MS4078
- MS-4078;MS 4078
- 1-Piperidineacetamide, 4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-N-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethyl]-
- 2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-5-isopropoxy-2-methylphenyl)piperidin-1-yl)-N-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)acetamide
- MS-4078,Anaplastic lymphoma kinase,CD246,Inhibitor,MS4078,ALK tyrosine kinase receptor,inhibit,Anaplastic lymphoma kinase (ALK),MS 4078,PROTACs,Cluster of differentiation 246
- MS4078, 10 mM in DMSO
- CAS:
- 2229036-62-6
- MF:
- C45H52ClN9O8S
- MW:
- 914.47
- Mol File:
- 2229036-62-6.mol
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MS4078 Chemical Properties
- Density
- 1.377±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 50 mg/mL (54.68 mM; Need ultrasonic)
- pka
- 10.74±0.40(Predicted)
- form
- Solid
- color
- Light yellow to yellow
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MS4078 Usage And Synthesis
Description
MS4078 is a heterobifunctional linker that binds to protein targets and delivers cytotoxic drugs to cancer cells. It has a selective binding affinity for cancer cells and has shown minimal toxicity in pre-clinical studies.
Uses
MS4078 is an inhibitor and PROTAC (degrader) of ALK.
MS4078Supplier
Shanghai Lollane Biological Technology Co.,Ltd.
- Tel
- 021-52996696，15000506266 15000506266
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 18892239720
- psaitong@jm-bio.com
Shanghai finete Pharmaceutical Co., Ltd.
- Tel
- 021-021-00000000 18221039705
- finetechpharm@126.com
Jilin Province Woda Biotechnology Co., Ltd.
- Tel
- 13504435624
- 1927928688@qq.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
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