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DYCLONINE

Basic information Safety Supplier Related

DYCLONINE Basic information

Product Name:
DYCLONINE
Synonyms:
  • DYCLONINE
  • 1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanon
  • 4’-butoxy-3-piperidino-propiophenon
  • dyclocaine
  • dyclonin
  • 4'-Butoxy-β-piperidinopropiophenone
  • Dyclonine HCI
  • 1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one
CAS:
586-60-7
MF:
C18H27NO2
MW:
289.41
EINECS:
1312995-182-4
Product Categories:
  • DYCLONE
Mol File:
586-60-7.mol
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DYCLONINE Chemical Properties

Boiling point:
424.5±25.0 °C(Predicted)
Density 
1.017±0.06 g/cm3(Predicted)
pka
8.68±0.10(Predicted)
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DYCLONINE Usage And Synthesis

Originator

Dyclone,Dow,US,1956

Uses

anesthetic (local)

Definition

ChEBI: N-Ethylpiperidine in which one of the hydrogens attached to the methyl group is substituted by a 4-butoxybenzoyl group.

Manufacturing Process

A mixture of 17.6 grams of p-n-butoxyacetophenone, 12.1 grams of piperidine hydrochloride, 4.5 grams paraformaldehyde, 0.25 cc concentrated hydrochloric acid, 52.5 cc nitroethane, 7.5 cc of 95% ethanol, and 15 cc of toluene was boiled under reflux for one hour, removing water formed in the reaction by means of a condensate trap. The mixture was then cooled. The crystals which formed were collected by filtration, washed with anhydrous ether and recrystallized from methyl ethyl ketone. The crystals thus obtained, which melted at 174-175°C, were shown by analysis to be 4-n-butoxy-β- piperidinopropiophenone hydrochloride.

brand name

Dyclone (AstraZeneca).

Therapeutic Function

Local anesthetic

DYCLONINESupplier

Shangchem Co., Ltd.
Tel
+86-21-68182121
Nanjing Sunlida Biological Technology Co., Ltd.
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025-57798810
Email
sales@sunlidabio.com
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Email
info@tsbiochem.com
Wuhan DKY Technology Co.,Ltd.
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27-81302488 18007166089
Email
info@dkybpc.com
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Email
sales@chem-strong.com