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CHRYSOERIOL

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CHRYSOERIOL Basic information

Product Name:
CHRYSOERIOL
Synonyms:
  • CHRYSOERIOL
  • 3'-METHOXY-5,7,4'-TRIHYDROXYFLAVONE
  • 4',5,7-TRIHYDROXY-3'-METHOXYFLAVON
  • 4',5,7-TRIHYDROXY-3'-METHOXYFLAVONE
  • 3’-methoxyapigenin
  • 3’-o-methyluteolin
  • 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4h-1-benzopyran-4-on
  • chryseriol
CAS:
491-71-4
MF:
C16H12O6
MW:
300.26
EINECS:
207-742-6
Product Categories:
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Tetra-substituted Flavones
Mol File:
491-71-4.mol
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CHRYSOERIOL Chemical Properties

Melting point:
>300°C (dec.)
Boiling point:
574.3±50.0 °C(Predicted)
Density 
1.512±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly, Heated and Sonicated)
form 
Solid
pka
6.49±0.40(Predicted)
color 
Yellow to Very Dark Yellow
Stability:
Hygroscopic
LogP
2.229 (est)
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CHRYSOERIOL Usage And Synthesis

Uses

Chrysoeriol is a methoxyflavonoid that selectively inhibits the formation of a carcinogenic estrogen metabolite in MCF-7 breast cancer cells. A metabolite of Luteolin (L475000).

Definition

ChEBI: The 3'-O-methyl derivative of luteolin.

target

ERK | p38 | Akt | PI3K | mTOR | p21 | AhR | P450 (e.g. CYP17) | NOS | NF-kB | AP-1 | ROS | Potassium Channel

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