Basic information Safety Supplier Related

N-Nitroso-N-Methyl-4-Aminobutyric Acid

Basic information Safety Supplier Related

N-Nitroso-N-Methyl-4-Aminobutyric Acid Basic information

Product Name:
N-Nitroso-N-Methyl-4-Aminobutyric Acid
Synonyms:
  • Losartan Impurity 17
  • NMBA
  • N-NITROSO-N-METHYL-4-AMINOBUTYRIC ACID
  • 4-(methylnitrosoamino)-butyricaci
  • 4-(n-nitroso-n-methylamino)butyricacid
  • n-methyl-n-(3-carboxypropyl)nitrosamine
  • 4-(N-NITROSOMETHYLAMINO)BUTYRICACID
  • 4-(Methylnitrosoamino)butanoic acid
CAS:
61445-55-4
MF:
C5H10N2O3
MW:
146.14
Product Categories:
  • Aliphatics
  • Nicotine Derivatives
Mol File:
61445-55-4.mol
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N-Nitroso-N-Methyl-4-Aminobutyric Acid Chemical Properties

Melting point:
>25 °C
Boiling point:
265.74°C (rough estimate)
Density 
1.3394 (rough estimate)
refractive index 
1.4954 (estimate)
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Soluble), Dichloromethane (Slightly), Ethyl Acetate (Slightly)
form 
Solid
pka
4.57±0.10(Predicted)
color 
Off-White to Yellow
Stability:
Hygroscopic
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N-Nitroso-N-Methyl-4-Aminobutyric Acid Usage And Synthesis

Chemical Properties

Yellow Oil

Definition

ChEBI: N-nitroso-N-methyl-4-aminobutyric acid is a nitrosamine that has methyl and 3-carboxypropyl substituents. It is a tobacco-derived nitrosamino acid that is a known animal and potential human carcinogen. It induces bladder transitional cell carcinomas in rats and has recently been identified as a contaminant in certain blood pressure medications. It has a role as a carcinogenic agent, a rat metabolite, a xenobiotic metabolite and a plant metabolite. It is a monocarboxylic acid and a nitrosamine.

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