N-Nitroso-N-Methyl-4-Aminobutyric Acid
N-Nitroso-N-Methyl-4-Aminobutyric Acid Basic information
- Product Name:
- N-Nitroso-N-Methyl-4-Aminobutyric Acid
- Synonyms:
-
- Losartan Impurity 17
- NMBA
- N-NITROSO-N-METHYL-4-AMINOBUTYRIC ACID
- 4-(methylnitrosoamino)-butyricaci
- 4-(n-nitroso-n-methylamino)butyricacid
- n-methyl-n-(3-carboxypropyl)nitrosamine
- 4-(N-NITROSOMETHYLAMINO)BUTYRICACID
- 4-(Methylnitrosoamino)butanoic acid
- CAS:
- 61445-55-4
- MF:
- C5H10N2O3
- MW:
- 146.14
- Product Categories:
-
- Aliphatics
- Nicotine Derivatives
- Mol File:
- 61445-55-4.mol
N-Nitroso-N-Methyl-4-Aminobutyric Acid Chemical Properties
- Melting point:
- >25 °C
- Boiling point:
- 265.74°C (rough estimate)
- Density
- 1.3394 (rough estimate)
- refractive index
- 1.4954 (estimate)
- storage temp.
- Hygroscopic, -20°C Freezer, Under Inert Atmosphere
- solubility
- Chloroform (Soluble), Dichloromethane (Slightly), Ethyl Acetate (Slightly)
- form
- Solid
- pka
- 4.57±0.10(Predicted)
- color
- Off-White to Yellow
- Stability:
- Hygroscopic
N-Nitroso-N-Methyl-4-Aminobutyric Acid Usage And Synthesis
Chemical Properties
Yellow Oil
Uses
N-Nitroso-N-methyl-4-aminobutyric acid EP reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.
It is also used to prepare N-Nitrosamines spiking solution to detect the concentration of N-nitrosamines in active substances by liquid chromatography coupled with mass spectrometry according to the monograph 20542of European Pharmacopoeia.
Definition
ChEBI: N-nitroso-N-methyl-4-aminobutyric acid is a nitrosamine that has methyl and 3-carboxypropyl substituents. It is a tobacco-derived nitrosamino acid that is a known animal and potential human carcinogen. It induces bladder transitional cell carcinomas in rats and has recently been identified as a contaminant in certain blood pressure medications. It has a role as a carcinogenic agent, a rat metabolite, a xenobiotic metabolite and a plant metabolite. It is a monocarboxylic acid and a nitrosamine.
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N-Nitroso-N-Methyl-4-Aminobutyric Acid(61445-55-4)Related Product Information
- 4-Aminobutyric acid
- N-NITROSO-N-METHYL-4-AMINOBUTYRIC ACID, METHYL ES
- N-Nitroso-N-Methyl-4-Aminobutyric Acid
- 3-carboxypropyl-(2-propenyl)nitrosamine
- butyl(3-carboxypropyl)nitrosamine
- N-NITROSOFOLICACID
- N-PROPYL-N-(3-CARBOXYPROPYL)NITROSAMINE
- N-AMYL-N-(3-CARBOXYPROPYL)NITROSAMINE
- 4-(methylnitrosamino)-4-(3-pyridyl)butyric acid
- BUTYRICACID,4-(BUTYLNITROSOAMINO)-3-HYDROXY-
- N-ETHYL-N-(3-CARBOXYPROPYL)NITROSAMINE
- N-(3-Carboxypropyl)-N-nitrosourea
- N-NITROSO-N-METHYL-4-AMINOBUTYRIC ACID, METHYL ESTER