CaCO2 Chemical Properties

storage temp. 

-196°C

form 

liquid

biological source

human colon

CaCO2 Usage And Synthesis

Uses

CACO-2 has been used in the cytotoxicity studies with high pressure-assisted extraction (HPE) fraction of nettle leaf extracts.
CACO-2 may be used as a cell model to study:

• in vitro permeability assay with various biopharmaceuticals
• in iron uptake and absorption studies
• in the cytotoxicity assay with surfactants and transporter inhibitors
• in liposome formulated drug uptake and cytotoxicity studies

Biochem/physiol Actions

Caco-2 (Cancer coli-2) is derived from colorectal adenocarcinoma and grows as an adherent monolayer of epithelial cells. Caco-2 cell line is a widely used intestinal epithelium model and has unique spontaneous differentiation and confluence property. It actively transports vitamins, hormones, amino acids and sugars. Caco-2 expresses various enzymes, ionic and non-ionic transporters similar to normal human epithelia. Caco-2 cell line models grow on filter support. They have simplicity and reproducibility and provide reliable information. Since Caco-2 mimics the intestinal epithelium, it is the preferred cell model for cytotoxic studies, food and drug transport studies.

CaCO2()Related Product Information

• Rat bone marrow-derived macrophages
• IMR 32
• 293 [HEK-293] human embryonic kidney cells
• Mouse intestinal mucosal epithelial cells
• Mouse neuroglia
• Mouse mesenteric smooth muscle cells
• Rat Schwann cells
• NCI-H1792
• RPMI 2650
• RT-112