Basic information Safety Supplier Related

D-(+)-Norephedrine

Basic information Safety Supplier Related

D-(+)-Norephedrine Basic information

Product Name:
D-(+)-Norephedrine
Synonyms:
  • (1S,2R)-(+)-2-AMINO-1-PHENYL-1-PROPANOL
  • (1S,2R)-2-AMINO-1-PHENYL-1-PROPANOL
  • (1S,2R)-(+)-PHENYLPROPANOLAMINE
  • (1S,2R)-(+)-NOREPHEDRINE
  • D-(+)-NOREPHEDRINE
  • ERYTHRO-ALPHA-(1-AMINOETHYL)BENZYL ALCOHOL
  • (1S,2R)-(+)-Norephedrine [DD]
  • D-(+)-Norephedrine [DD]
CAS:
37577-28-9
MF:
C9H13NO
MW:
151.21
EINECS:
628-077-1
Product Categories:
  • Pharmaceutical Intermediates
Mol File:
37577-28-9.mol
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D-(+)-Norephedrine Chemical Properties

Melting point:
51-54 °C(lit.)
alpha 
40 º (c=7, 1M HCl)
Boiling point:
288.1±20.0 °C(Predicted)
Density 
1.071±0.06 g/cm3(Predicted)
Flash point:
>230 °F
storage temp. 
2-8°C
pka
12.07±0.45(Predicted)
optical activity
[α]20/D +40°, c = 7 in 1 M HCl
BRN 
2802896
CAS DataBase Reference
37577-28-9(CAS DataBase Reference)
NIST Chemistry Reference
(1S,2r)-(+)-norephedrine(37577-28-9)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
WGK Germany 
3
3-8-10

MSDS

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D-(+)-Norephedrine Usage And Synthesis

Uses

(1S,2R)-(+)-Norephedrine Hydrochloride is used in preparation of pyrrolopyridines as ERK inhibitors useful in treatment of diseases.

Definition

ChEBI: (+)-norephedrine is an amphetamine that is propylbenzene substituted by a hydroxy group at position 1 and by an amino group at position 2 (the 1S,2R-stereoisomer). It is a member of amphetamines and a phenethylamine alkaloid.

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