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CIS-8,11,14-EICOSATRIENOIC ACID

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CIS-8,11,14-EICOSATRIENOIC ACID Basic information

Product Name:
CIS-8,11,14-EICOSATRIENOIC ACID
Synonyms:
  • DIHOMO-GAMMA-LINOLENIC ACID
  • DIHOMO-GAMMA-LINOLENIC ACID-CONTAINING TRIGLYCERIDE
  • EICOSA-8Z,11Z,14Z-TRIENOIC ACID
  • CIS,CIS,CIS-8,11,14-EICOSATRIENOIC ACID
  • CIS-8,11,14-EICOSATRIENOIC ACID
  • DELTA 8 CIS 11 CIS 14 CIS EICOSATRIENOIC ACID
  • DGLA
  • HOMO-GAMMA-LINOLENIC ACID
CAS:
1783-84-2
MF:
C20H34O2
MW:
306.48
EINECS:
217-233-0
Product Categories:
  • Aliphatics
  • Fatty Acid Derivatives & Lipids
  • Glycerols
Mol File:
1783-84-2.mol
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CIS-8,11,14-EICOSATRIENOIC ACID Chemical Properties

Boiling point:
200°C(lit.)
Density 
0.917±0.06 g/cm3(Predicted)
refractive index 
n20/D 1.478(lit.)
Flash point:
144 °F
storage temp. 
-20°C
solubility 
chloroform: 50 mg/mL, clear, colorless
form 
Liquid
pka
4.77±0.10(Predicted)
color 
Colourless to Light Yellow
BRN 
1796533
Stability:
Light Sensitive
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Safety Information

Safety Statements 
23-24/25
RIDADR 
NA 1993 / PGIII
WGK Germany 
3
RTECS 
JX3880000
8-10-23
HS Code 
2916.19.3000

MSDS

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CIS-8,11,14-EICOSATRIENOIC ACID Usage And Synthesis

Description

Dihomo-γ-linolenic acid (DGLA) is a 20-carbon ω?6 fatty acid. In physiological literature, it is given the name 20:3 (ω?6). DGLA is a carboxylic acid with a 20-carbon chain and three cis double bonds; the first double bond is located at the sixth carbon from the omega end. DGLA is the elongation product of γ-linolenic acid (GLA; 18:3, ω?6). GLA, in turn, is a desaturation product of linoleic acid (18:2, ω?6). DGLA is made in the body by the elongation of GLA, by an efficient enzyme which does not appear to suffer any form of (dietary) inhibition. DGLA is an extremely uncommon fatty acid, found only in trace amounts in animal products.

Chemical Properties

Clear Colourless Oil

Uses

cis-8,11,14-Eicosatrienoic acid may be used as an analytical reference standard for the determination of the analyte in plant species and biological matrices by chromatography-based techniques.

Uses

cis-8,11,14-Eicosatrienoic acid is a fatty acid which has selective tumoricidal action.

Definition

ChEBI: An icosatrienoic acid having three cis double bonds at positions 8, 11 and 14.

General Description

cis-8,11,14-Eicosatrienoic acid is an unsaturated fatty acid, present in various plant species including Echium Rauwolfii, Sisymbrium Irio, Rhytididelphus squarrosus (Hedw.) Warnst etc, which are of pharmaceutical interest.

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