HSP27, HUMAN Chemical Properties

storage temp. 

-70°C

form 

buffered aqueous solution

biological source

rabbit

Safety Information

Safety Statements 

23-24/25

WGK Germany 

nwg

HS Code 

3504009000

Storage Class

10 - Combustible liquids

HSP27, HUMAN Usage And Synthesis

Uses

Anti-HSP27 Antibody detects endogenous levels of total HSP27 protein.

Description

Recombinant Human HSP-27 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 205 amino acids and having a molecular mass of 22.7 kDa. Hsp27 was over-expressed in E. coli and purified by conventional chromatography.

Source

Escherichia Coli

Background

HSP27 (also known as the Estrogen-Regulated 24K protein, and hsp 28) is a member of the mammalian small heat shock protein family. Hsp27 is expressed constitutively in many tissues and its expression is increased to high levels after various types of stress including elevated temperatures, toxic metals, drugs and oxidants. Also, Hsp27 is phosphorylated in vivo on three phosphorylation sites (Ser15, Ser78 and Ser82) by protein kinases including MAPKAP kinase 2 and the stress-activated protein kinase SAPK2 (p38).