L-3-Cyanophenylalanine Chemical Properties

Boiling point:

325.7°C (rough estimate)

Density 

1.2167 (rough estimate)

refractive index 

1.6300 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

Powder

pka

2.14±0.10(Predicted)

color 

White to slightly yellow

CAS DataBase Reference

57213-48-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22

Safety Statements 

26-37/39-37/38

RIDADR 

UN3439

HazardClass 

6.1

PackingGroup 

III

HS Code 

29225090

MSDS

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L-3-Cyanophenylalanine Usage And Synthesis

Chemical Properties

white to slightly yellow powder

Uses

H-Phe(3-CN)-OH is a phenylalanine derivative[1].

Antimicrobial activity

L-3-Cyanophenylalanine (3CP) is a β-amino acid that has been shown to have an interaction with serine protease. 3CP is an antibacterial agent that is used in the treatment of bacterial infections. It has been shown to inhibit the growth of bacteria by inhibiting the acid transporter, which leads to a decrease in intracellular pH. 3CP binds to the basic group of the enzyme and forms a covalent bond, inhibiting its function. The synthesis of 3CP can be achieved through synthetic chemistry or by enzymatic conversion from L-serine. This compound can also be obtained as an enantiomer, meaning it has two different forms: one that is active and one that is inactive.

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-828. DOI:10.1080/10408398.2012.708368

L-3-Cyanophenylalanine(57213-48-6)Related Product Information

• DL-Phenylalanine
• D-Phenylalanine
• L-Phenylalanine
• Phenprobamate
• 3-(4-acetylphenyl)-2-aminopropanoic acid hydrochloride
• 3-METHOXY-L-PHENYLALANINE
• (S)-2-AMino-3-(3-iodophenyl)propanoic acid
• 3-Methylphenyl-L-alanine
• L-3-Chlorophenylalanine
• 2-Chloro-L-phenylalanine
• L-2-Bromophenylalanine
• L-Penicillamine
• 2-FLUORO-L-PHENYLALANINE
• H-Phe(2-F)-OH·HCl
• 2-Methylphenyl-L-alanine
• H-Phe(4-Br)-OEt·HCl
• 3-Bromo-L-phenylalanine
• (2S)-2-amino-3-(3-carbamoylphenyl)propanoic acid