Biphenyl dimethyl dicarboxylate Chemical Properties

Melting point:

213-215 °C (lit.)

Boiling point:

373.4°C (rough estimate)

Density 

1.2117 (rough estimate)

refractive index 

1.5447 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Benzene (Slightly, Heated, Sonicated), Chloroform (Slightly, Heated, Sonicated)

form 

Solid

color 

White to Off-White

Water Solubility 

Insoluble in water.

BRN 

2055852

CAS DataBase Reference

792-74-5(CAS DataBase Reference)

NIST Chemistry Reference

[1,1'-Biphenyl]-4,4'-dicarboxylic acid, dimethyl ester(792-74-5)

EPA Substance Registry System

[1,1'-Biphenyl]-4,4'-dicarboxylic acid, dimethyl ester (792-74-5)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

TSCA 

Yes

HS Code 

29173990

Hazardous Substances Data

792-74-5(Hazardous Substances Data)

MSDS

• Language:English Provider:[1,1'-Biphenyl]-4,4'-dicarboxylic acid dimethyl ester
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Biphenyl dimethyl dicarboxylate Usage And Synthesis

Chemical Properties

White or cream crystalline powder

Uses

Dimethyl biphenyl-4,4'-dicarboxylate is used as a hepatoprotectant in the treatment of chronic hepatitis. At 250 μg/ml, it has been shown to stimulate JAK/STAT signaling and to induce the expression of interferon-α stimulated genes in a HepG2 cell line. It has been used to study hepatic fibrosis and chronic hepatocellular damage. It appears to normalize alanine aminotransferase (ALT) in cases where levels of ALT are elevated. It may be employed as starting reagent for the synthesis of dimethyl 2-fluoro-and 2,2?-difluorobiphenyl-4,4?-dicarboxylates.

Synthesis Reference(s)

Tetrahedron Letters, 18, p. 4089, 1977 DOI: 10.1016/S0040-4039(01)83434-1

General Description

Dimethyl biphenyl-4,4′-dicarboxylate is a planar biphenyldicarboxylic acid ester. Crystal data of dimethyl biphenyl-4, 4′-dicarboxylate has been reported.

Biphenyl dimethyl dicarboxylate(792-74-5)Related Product Information

• N,N-Dimethylformamide
• 4,4'-Diacetylbiphenyl
• Dimethyl carbonate
• 4,4'-Ethylenedianiline
• Biphenyl-4,4'-dicarboxylic acid
• Dimethyl sulfoxide
• Biphenyl
• DIETHYL BIPHENYL-4,4'-DICARBOXYLATE
• Dimethyl terephthalate
• Dimethyl Glutarate
• 4,4'-Dimethylbiphenyl
• ETHANE
• Dimethyl phthalate
• Dimethyl sulfide
• Benzidine
• Dimethyl fumarate
• Dimethyl ether
• Dimethyl isophthalate