IFN-G R 1 HUMAN
IFN-G R 1 HUMAN Basic information
- Product Name:
- IFN-G R 1 HUMAN
- Synonyms:
-
- Anti-Interferon-γ Receptor α chain antibody produced in rabbit
- CD119 antigen
- INTERFERON-G RECEPTOR 1 HUMAN
- IFN-G R 1 HUMAN
- IFN-γ R 1
- Interferon-γ Receptor 1 human
- IFNAR
- interferon-α/β receptor α chain
- MW:
- 0
- Mol File:
- Mol File
IFN-G R 1 HUMAN Chemical Properties
- storage temp.
- −20°C
- form
- lyophilized powder
- biological source
- rabbit
MSDS
- Language:English Provider:SigmaAldrich
IFN-G R 1 HUMAN Usage And Synthesis
Uses
Anti-Interferon-γ Receptor α chain Antibody detects endogenous levels of total Interferon-γ Receptor α chain protein.
Description
IFNGR1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 234 amino acids (18-245a.a.) and having a molecular mass of 26.6kDa (Migrates at 28-40kDa on SDS-PAGE under reducing conditions).
IFNGR1 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Source
Sf9, Baculovirus cells
Background
IFNGR1 is a part of the hematopoietic cytokine receptor superfamily. IFNGR1 forms a site that is recognized by the extracellular domain of IFNGR2 by inducing the rapid dimerization of chains. IFNGR1 Plays an important role in the IFN-gamma pathway that is essential for the cellular response to infectious agents. IFNGR1 is expressed in a membrane-bound form in various cells, and is over-expressed in tumor cells.