TRI(2-FURYL)PHOSPHINE
TRI(2-FURYL)PHOSPHINE Basic information
- Product Name:
- TRI(2-FURYL)PHOSPHINE
- Synonyms:
-
- SALOR-INT L308749-1EA
- TRIS(2-FURYL)PHOSPHINE
- TRI(2-FURYL)PHOSPHINE
- Tri(2-furyl)phospine
- Tri(2-furyl)phosphine,97%
- Tri(2-furyL
- TFP / Tri(2-furyl)phosphine
- Tri(fur-2-yl)phosphine
- CAS:
- 5518-52-5
- MF:
- C12H9O3P
- MW:
- 232.17
- EINECS:
- 628-036-8
- Product Categories:
-
- Achiral Phosphine
- Aryl Phosphine
- organophosphorus ligand
- Aromatics
- Chelating Agents & Ligands
- Heterocycles
- Ligand
- Phosphine Ligands
- Synthetic Organic Chemistry
- Catalysis and Inorganic Chemistry
- Phosphine Ligands
- Phosphorus Compounds
- Mol File:
- 5518-52-5.mol
TRI(2-FURYL)PHOSPHINE Chemical Properties
- Melting point:
- 59-64 °C (lit.)
- Boiling point:
- 136 °C/4 mmHg (lit.)
- Flash point:
- 136°C/4mm
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- solid
- color
- faintly brown
- Sensitive
- air sensitive
- BRN
- 1577564
- InChI
- InChI=1S/C12H9O3P/c1-4-10(13-7-1)16(11-5-2-8-14-11)12-6-3-9-15-12/h1-9H
- InChIKey
- DLQYXUGCCKQSRJ-UHFFFAOYSA-N
- SMILES
- P(C1=CC=CO1)(C1=CC=CO1)C1=CC=CO1
- CAS DataBase Reference
- 5518-52-5(CAS DataBase Reference)
MSDS
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
TRI(2-FURYL)PHOSPHINE Usage And Synthesis
Reaction
- Useful ligand for C-C coupling reactions.
- Ligand used for the alkynylation of thioesters.
- Ligand used for enol ester formation.
- Ligand for palladium-catalyzed 3-Component coupling.
- Ligand for palladium-catalyzed C-C coupling reaction.
- Ligand for trans-olefin formation.
- Olefin formation from N-tosylhydrazones and benzyl halides.
- C-H arylation/alkenylation of 1-substituted tetrazoles.
Chemical Properties
TRI(2-FURYL)PHOSPHINE is white to light yellow crystal powde
Uses
TRI(2-FURYL)PHOSPHINE is a phopshine ligand used in transition-metal mediated organic synthesis, in particular in wittig reactions to improved (Z) selectivity.
Uses
suzuki reaction
reaction suitability
reagent type: ligand
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reagent type: ligand
reaction type: Cycloisomerizations
reagent type: ligand
reaction type: Heck Reaction
reagent type: ligand
reaction type: Negishi Coupling
reagent type: ligand
reaction type: Oxidations
reagent type: ligand
reaction type: Sonogashira Coupling
reagent type: ligand
reaction type: Stille Coupling
reagent type: ligand
reaction type: Suzuki-Miyaura Coupling
Synthesis
The reaction flask was replaced with nitrogen atmosphere, under mechanical stirring, 20g of analytically pure furan, 34.8g of analytically pure TMEDA and 140mL of n-hexane were added into the reaction flask, 120mL of n-butyllithium (analytically pure) with a concentration of 2.5M/L was added dropwise at room temperature, after the dropwise addition was completed, the temperature was elevated to 50?? and kept at 2h.
An analytically pure solution of 8g of n-hexane with a concentration of 3.5M/L of n-butyllithium (analytically pure) was added dropwise at 0?? and kept at this temperature for 1h.
The reaction solution was poured into 200mL of saturated aqueous ammonium nitrate solution at 0??, and stirred thoroughly, then the reaction solution was static stratified, and the organic phase was separated, and the aqueous phase was extracted with dichloromethane for 2-3 times, and the organic phase was combined, and the organic phase was concentrated to get the crude product, which was recrystallized with petroleum ether to get the crude product, and the crude product was extracted with petroleum ether to get the crude product, and the organic phase was concentrated to get the crude product. Recrystallized with petroleum ether, obtained white crystal product tris(2-furyl)phosphine 11.1g, the calculated yield was 82%, through the Agilent 1100 liquid chromatograph to get the product purity of 99.1%
.TRI(2-FURYL)PHOSPHINESupplier
- Tel
- 131-21959385 18804271668
- chemrocking@bjgreenchem.com
- Tel
- 18210857532; 18210857532
- jkinfo@jkchemical.com
- Tel
- 4006356688 18621169109
- market03@meryer.com
- Tel
- +49 3493/605464
- sales@intatrade.de
- Tel
- 400-6106006
- saleschina@alfa-asia.com
TRI(2-FURYL)PHOSPHINE(5518-52-5)Related Product Information
- Tris(4-fluorophenyl)phosphine
- tris(2-fluorophenyl)phosphane
- PHOSPHOROUS ACID TRI-O-CRESYL ESTER
- tris(2-carboxaldehyde)triphenylphosphine
- Trimethyl 3,3',3''-phosphinetriyltripropanoate hydrochloride
- TRI(2,5-XYLYL)PHOSPHINE
- Tri(o-tolyl)phosphine
- TRI-P-TOLYLPHOSPHINE
- TRIS(3,5-DIMETHYLPHENYL)PHOSPHINE
- TRIS(3-FLUOROPHENYL)PHOSPHINE
- TRIS(2-CYANOETHYL)PHOSPHINE
- Phosphine
- TRI(2-FURYL)PHOSPHINE
- BIS(2-FURYL)PHOSPHINE
- Tri(3-furyl)phosphine sulfide
- Tri(3-furyl)phosphine oxide
- Tri(2-furyl)phosphine oxide
- Tri(3-furyl)phosphine