Basic information Safety Supplier Related

CHOLESTERYL ARACHIDONATE

Basic information Safety Supplier Related

CHOLESTERYL ARACHIDONATE Basic information

Product Name:
CHOLESTERYL ARACHIDONATE
Synonyms:
  • CHOLESTERYL EICOSATETRAENOATE
  • CHOLESTERYL ARACHIDONATE
  • 3BETA-HYDROXY-5-CHOLESTENE 3-ARACHIDONATE
  • 5-CHOLESTEN-3BETA-OL 3-ARACHIDONATE
  • 3β-hydroxy-5-cholestene 3-arachidonate
  • [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
  • Cholesteryl arachidonic acid
  • 3β-Hydroxy-5-cholestene 3-arachidonate, 5-Cholesten-3β-ol 3-arachidonate, Cholesteryl eicosatetraenoate
CAS:
604-34-2
MF:
C47H76O2
MW:
673.11
Mol File:
604-34-2.mol
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CHOLESTERYL ARACHIDONATE Chemical Properties

Melting point:
19 °C
Boiling point:
697.9±54.0 °C(Predicted)
Density 
0.97±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
viscous liquid
color 
clear
Stability:
Light Sensitive
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Safety Information

WGK Germany 
3
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CHOLESTERYL ARACHIDONATE Usage And Synthesis

Description

Cholesteryl arachidonate is a cholesterol ester that is found in plasma and the adrenal gland. It is a component of low-density lipoprotein (LDL) and oxidiation of the arachidonate moiety contributes to macrophage activation and foam cell formation in atherosclerosis. Cholesteryl arachidonate undergoes hydrolysis to release arachidonic acid during ACTH-stimulated prostaglandin synthesis in rat adrenocortical cells. Levels of cholesteryl arachidonate are increased in the bronchoalveolar lavage fluid (BALF) in pediatric cystic fibrosis patients compared to healthy controls as well as in placentas of women with chorioamnionitis.

Uses

Cholesteryl arachidonate is a cholesterol ester found associated with the neutral core of low density lipoprotein.

Definition

ChEBI: A cholesterol ester obtained by the formal condensation of the hydroxy group in cholesterol with the carboxy group of arachidonic acid.

CHOLESTERYL ARACHIDONATESupplier

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