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METHYL ARACHIDONATE

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METHYL ARACHIDONATE Basic information

Product Name:
METHYL ARACHIDONATE
Synonyms:
  • METHYL ARACHIDONATE, >=99% (GC)
  • 5Z,8Z,11Z,14Z-EICOSATETRAENOIC ACID, METHYL ESTER
  • ALL CIS-5,8,11,14-EICOSATETRAENOIC ACID METHYL ESTER
  • DELTA 5 CIS 8 CIS 11 CIS 14 CIS EICOSATETRAENOIC ACID METHYL ESTER
  • C20:4 (ALL CIS-5,8,11,14) METHYL ESTER
  • ARACHIDONIC ACID METHYL ESTER
  • METHYL ARACHIDONATE
  • 11,14-eicosatetraenoicacid,methylester,(all-z)-8
CAS:
2566-89-4
MF:
C21H34O2
MW:
318.49
EINECS:
219-900-1
Product Categories:
  • Fatty AcidsUnsaturated fatty acids and derivatives
  • Esters
  • FAMEs
  • Lipid Analytical Standards
  • Methyl EstersFA/FAME/Lipids/Steroids
  • Neats&Single Component Solutions
  • Other Lipid Related Products
Mol File:
2566-89-4.mol
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METHYL ARACHIDONATE Chemical Properties

Boiling point:
200-205℃ (1-2 Torr)
Density 
0.9168 g/cm3
refractive index 
1.4875 (589.3 nm 20℃)
storage temp. 
2-8°C
solubility 
chloroform: 50 mg/mL, clear, colorless
form 
Liquid
color 
Colourless
BRN 
1714445
Stability:
Light Sensitive
LogP
7.466 (est)
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Safety Information

Hazard Codes 
F,Xn,N
Risk Statements 
19-67-65-50/53-38-11
Safety Statements 
9-16-29-33-60-61-62
RIDADR 
UN 3183 4.2/PG 3
WGK Germany 
3
10-21-23
HazardClass 
4.2
PackingGroup 
I

MSDS

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METHYL ARACHIDONATE Usage And Synthesis

Uses

Arachidonic acid is the keystone essential fatty acid at the origin of the arachidonic acid cascade. It is converted by cyclooxygenase, lipoxygenase, and epoxygenase enzymes into more than one hundred fifty different potent primary autacoid metabolites in species ranging from fungi to plants to mammals. Arachidonic acid is stored in tissue phospholipids in esterified form, where it comprises a small but critically controlled percentage of the polyunsaturated fatty acid pool. Arachidonic acid content is frequently measured by the saponification of the lipid fraction followed by methyl esterification and gas chromatographic analysis of the resulting FAME (fatty acid methyl ester) compounds. Arachidonic acid methyl ester can also be incorporated into dietary regimens or fed to cultured cells as a source of exogenous arachidonate.

Definition

ChEBI: A fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol.

Biochem/physiol Actions

Unlike most unsaturated fatty acid methyl esters, methyl arachidonate is a potent activator of protein kinase C at 5?50?μM. At the low end of the effective concentration range, the effect is due to cyclooxygenase products, while lipoxygenase products mediate the effect at higher concentrations.

METHYL ARACHIDONATE Preparation Products And Raw materials

Preparation Products

METHYL ARACHIDONATESupplier

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