N-Desethylsunitinib hydrochloride Chemical Properties

form 

Solid

color 

Yellow to brown

N-Desethylsunitinib hydrochloride Usage And Synthesis

Uses

(E/Z)-N-Desethylsunitinib hydrochloride ((E/Z)-SU-12662 hydrochloride) is a compound with potential anti-tumor activity that inhibits VEGF-R2 and PDGF-Rβ tyrosine kinases. (E/Z)-N-Desethylsunitinib hydrochloride is the main active metabolite of sunitinib and has the ability to competitively inhibit ATP[1].

References

[1] Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase DOI:10.1021/jm0204183

N-Desethylsunitinib hydrochloride(1261432-05-6)Related Product Information

• N-Desethyl Sunitinib