ChemicalBook > Product Catalog > Organic Chemistry > Carboxylic acids and derivatives > Cyclic carboxylic acids > PROTAC Linker 27
PROTAC Linker 27
PROTAC Linker 27 Basic information
- Product Name:
- PROTAC Linker 27
- Synonyms:
-
- PROTAC Linker 27
- Tos-PEG2-NH2
- 2-(2-aminoethoxy)ethyl 4-methylbenzenesulfonate
- Ethanol, 2-(2-aminoethoxy)-, 1-(4-methylbenzenesulfonate)
- CAS:
- 1246286-33-8
- MF:
- C11H17NO4S
- MW:
- 259.32
- Product Categories:
-
- peg
- Mol File:
- 1246286-33-8.mol
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PROTAC Linker 27 Chemical Properties
- Boiling point:
- 414.5±30.0 °C(Predicted)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- pka
- 8?+-.0.10(Predicted)
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PROTAC Linker 27 Usage And Synthesis
Biological Activity
Tos-PEG2-NH2 (PROTAC Linker 27) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
PROTAC Linker 27Supplier
TargetMol Chemicals Inc.
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Xi'an Qiyue Biotechnology Co., Ltd.
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